Antimicrobial Resistance in Qatar: Prevalence and Trends before and Amidst the COVID-19 Pandemic
Author | Al Mana, Hassan |
Author | Abdel Hadi, Hamad |
Author | Wilson, Godwin |
Author | Almaslamani, Muna A. |
Author | Abu Jarir, Sulieman H. |
Author | Ibrahim, Emad |
Author | Eltai, Nahla O. |
Available date | 2024-06-25T09:15:41Z |
Publication Date | 2024-03-01 |
Publication Name | Antibiotics |
Identifier | http://dx.doi.org/10.3390/antibiotics13030203 |
Citation | Al Mana, H.; Abdel Hadi, H.; Wilson, G.; Almaslamani, M.A.; Abu Jarir, S.H.; Ibrahim, E.; Eltai, N.O. Antimicrobial Resistance in Qatar: Prevalence and Trends before and Amidst the COVID-19 Pandemic. Antibiotics 2024, 13, 203. https://doi.org/10.3390/antibiotics13030203 |
Abstract | Antimicrobial resistance (AMR) is a global healthcare challenge with substantial morbidity, mortality, and management costs. During the COVID-19 pandemic, there was a documented increase in antimicrobial consumption, particularly for severe and critical cases, as well as noticeable travel and social restriction measures that might influenced the spectrum of AMR. To evaluate the problem, retrospective data were collected on bacterial infections and antimicrobial susceptibility patterns in Qatar before and after the pandemic from 1 January 2019 to 31 December 2021, covering 53,183 pathogens isolated from reported infection episodes. The findings revealed a significant resistance pattern for extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-EBC), carbapenem-resistant Enterobacteriaceae (CR-EBC), and carbapenem-resistant Pseudomonas aeruginosa (CRPA), ciprofloxacin-resistant Salmonella and methicillin-resistant Staphylococcus aureus (MRSA). For correlation with social restrictions, ESBL-EBC and MRSA were positively correlated with changing patterns of international travel (ρ = 0.71 and 0.67, respectively; p < 0.05), while CRPA was moderately correlated with the number of COVID-19 hospitalized patients (ρ = 0.49; p < 0.05). CREBC and CRPA respiratory infections were associated with hospitalized patients (OR: 3.08 and 2.00, respectively; p < 0.05). The findings emphasize the challenges experienced during the COVID-19 pandemic and links to international travel, which probably will influence the local epidemiology of AMR that needs further surveillance and control strategies. |
Sponsor | The study was conducted in accordance with the Declaration of Helsinki, and approved by the Institutional Review Board Ethics Committee of Hamad General Hospital, Medical Research Centre (MRC) (Protocol code: MRC-02-21-949) on 29 December 2021. and date of approval).” The study and collaboration were approved by the Medical Research Centre (MRC) of Hamad Medical Corporation (HMC), which abides by local and international research standards (Protocol: MRC-02-21-949). The study also received approval from the Ethical Committee and Institution Review Board of the MRC after observing data management and sharing standards, including limited access to nominated primary investigators, data anonymity, and governance. All shared data had no traced patients’ identification. |
Language | en |
Publisher | MDPI |
Subject | AMR bacterial co-infection COVID-19 hospital Qatar |
Type | Article |
Issue Number | 3 |
Volume Number | 13 |
ESSN | 2079-6382 |
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