Differences in oxidative stress profile in adolescents smoking waterpipe versus cigarettes: The Irbid TRY Project
Date
2020Metadata
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Waterpipe (Wp) tobacco smoking is widely spreading, especially among adolescents. It has also been associated with organ damage and disease risk resulting from oxidative stress. However, no studies have examined the effect of smoking Wp on oxidative stress among adolescents. In the current study, we evaluated serum levels of oxidative stress biomarkers and activities of antioxidant enzymes between adolescents smoking cigarette (Cg only), Wp only, both (CgWp) versus never. The results showed higher GSSG levels in the Cg only, Wp only, and CgWp versus the none group. Similarly, the activity of GPx was greater in the Cg only versus the Wp only and CgWp. The activity of catalase was higher in the Wp only/CgWp groups versus none. No main effect of smoking on GSH, or GSH/GSSH, SOD, or TBARS was detected. In conclusion, Wp smoking among adolescents is associated with induction of stress oxidative to a similar extend of Cg smoking. Interventions and studies for smoking cessation and harm reduction that target Wp smoking among adolescents are needed.
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