Browsing Biomedical Research Center by Author "Al-Khelaifi, Fatima"
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The association of HFE gene H63D polymorphism with endurance athlete status and aerobic capacity: novel findings and a meta-analysis.
Semenova, Ekaterina A; Miyamoto-Mikami, Eri; Akimov, Egor B; Al-Khelaifi, Fatima; Murakami, Haruka; Zempo, Hirofumi; Kostryukova, Elena S; Kulemin, Nikolay A; Larin, Andrey K; Borisov, Oleg V; Miyachi, Motohiko; Popov, Daniil V; Boulygina, Eugenia A; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Pushkarev, Vladimir P; Dyatlov, Dmitry A; Lekontsev, Eugene V; Pushkareva, Yuliya E; Andryushchenko, Liliya B; Elrayess, Mohamed A; Generozov, Edward V; Fuku, Noriyuki; Ahmetov, Ildus I... more authors ... less authors ( Springer , 2020 , Article)Iron is an important component of the oxygen-binding proteins and may be critical to optimal athletic performance. Previous studies have suggested that the G allele of C/G rare variant (rs1799945), which causes H63D amino ... -
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.
Al-Khelaifi, Fatima; Yousri, Noha A; Diboun, Ilhame; Semenova, Ekaterina A; Kostryukova, Elena S; Kulemin, Nikolay A; Borisov, Oleg V; Andryushchenko, Liliya B; Larin, Andrey K; Generozov, Edward V; Miyamoto-Mikami, Eri; Murakami, Haruka; Zempo, Hirofumi; Miyachi, Motohiko; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Fuku, Noriyuki; Abraham, David; Hingorani, Aroon; Donati, Francesco; Botrè, Francesco; Georgakopoulos, Costas; Suhre, Karsten; Ahmetov, Ildus I; Albagha, Omar; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2020 , Article)The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ... -
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
Al-Khelaifi, Fatima; Diboun, Ilhame; Donati, Francesco; Botre, Francesco; Abraham, David; Hingorani, Aroon; Albagha, Omar; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A... more authors ... less authors ( Nature Research , 2019 , Article)Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ... -
Metabolic profiling of elite athletes with different cardiovascular demand
Al-Khelaifi, Fatima; Donati, Francesco; Botrè, Francesco; Latiff, Aishah; Abraham, David; Hingorani, Aroon; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A; Elrayess, Mohamed A... more authors ... less authors ( John Wiley & Sons Ltd , 2019 , Article)Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ... -
Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
Al-Muraikhy, Shamma; Sellami, Maha; Domling, Alexander S; Rizwana, Najeha; Agouni, Abdelali; Al-Khelaifi, Fatima; Donati, Francesco; Botre, Francesco; Diboun, Ilhame; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2021 , Article)Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim ...