Browsing Biomedical Research Center by Author "Cyprian, Farhan"
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Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.
Cyprian, Farhan S; Al-Farsi, Halema F; Vranic, Semir; Akhtar, Saghir; Al Moustafa, Ala-Eddin ( Frontiers Media , 2018 , Article Review)Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ... -
HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
Cyprian, Farhan S; Al-Antary, Noor; Al Moustafa, Ala-Eddin ( Taylor & Francis , 2018 , Article)Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer ... -
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity.
Elrayess, Mohamed A; Cyprian, Farhan S; Abdallah, Abdallah M; Emara, Mohamed M; Diboun, Ilhame; Anwardeen, Najeha; Schuchardt, Sven; Yassine, Hadi M... more authors ... less authors ( Frontiers Media , 2022 , Article)Increased COVID-19 disease severity is higher among patients with type 2 diabetes mellitus and hypertension. However, the metabolic pathways underlying this association are not fully characterized. This study aims to ... -
Snornas and mirnas networks underlying covid-19 disease severity
Parray, Aijaz; Mir, Fayaz A.; Doudin, Asmma; Iskandarani, Ahmad; Danjuma, Ibn M.; Kuni, Rahim A.; Abdelmajid, Alaaedin; Abdelhafez, Ibrahim; Arif, Rida; Mulhim, Mohammad; Abukhattab, Mohammad; Dar, Shoukat R.; Moustafa, Ala-Eddin A.; Elkord, Eyad; Al Khal, Abdul L.; Elzouki, Abdel-Naser; Cyprian, Farhan... more authors ... less authors ( MDPI , 2021 , Article)There is a lack of predictive markers for early and rapid identification of disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers ... -
The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells
Kheraldine, Hadeel; Gupta, Ishita; Cyprian, Farhan; Vranic, Semir; Al Moustafa, Ala-Eddin ( Qatar University Press , 2021 , Poster)Introduction: Both Dasatinib (DA), a tyrosine kinase inhibitor that is used for targeted cancer therapy, and programmed death-ligand 1 (PD-1/PD-L1) inhibitor that is an immune checkpoint therapy, play a vital role in the ... -
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
Smatti, Maria K; Cyprian, Farhan S; Nasrallah, Gheyath K; Al Thani, Asmaa A; Almishal, Ruba O; Yassine, Hadi M... more authors ... less authors ( MDPI , 2019 , Article)For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...