Browsing Biomedical Research Center by Title
Now showing items 655-674 of 727
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The eutherian pseudoautosomal region
( S. Karger AG , 2016 , Article Review)The pseudoautosomal region (PAR) is a unique segment of sequence homology between differentiated sex chromosomes where recombination occurs during meiosis. Molecular and functional properties of the PAR are distinctive ... -
The Immunomodulatory Role of Microbiota in Rheumatic Heart Disease: What Do We Know and What Can We Learn from Other Rheumatic Diseases?
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article Review)Rheumatic heart disease (RHD) represents a serious cardiac sequela of acute rheumatic fever, occurring in 30-45% of patients. RHD is multifactorial, with a strong familial predisposition and known environmental risk factors ... -
The Implementation of an Integrated Management System at Qatar Biobank
( Mary Ann Liebert Inc. , 2019 , Article)Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, ... -
The landscape of genetic variations in non-syndromic primary ovarian insufficiency in the MENA region: a systematic review
( Frontiers Media SA , 2023 , Article Review)Introduction: Premature ovarian insufficiency (POI) is a primary cause of infertility with variable clinical manifestations. POI is a multifactorial disease with both environmental and known genetic etiologies, but data ... -
The power of phytochemicals combination in cancer chemoprevention
( Ivyspring International Publisher , 2020 , Article Review)Conventional therapies for cancer treatment have posed many challenges, including toxicity, multidrug resistance and economic expenses. In contrast, complementary alternative medicine (CAM), employing phytochemicals have ... -
The QChip1 knowledgebase and microarray for precision medicine in Qatar
( Nature Research , 2022 , Article)Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically population-private. The goal was to develop "QChip1," an inexpensive ... -
The Spectrum of Antibiotic Prescribing during COVID-19 Pandemic: A Systematic Literature Review
( Mary Ann Liebert Inc. , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients' adverse events and antimicrobial resistance (AMR) to the ... -
The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases
( Springer Science and Business Media Deutschland GmbH , 2022 , Article Review)Chromosomal translocations (CTs) are the most common type of structural chromosomal abnormalities in humans. CTs have been reported in several studies in the Arab world, but the frequency and spectrum of these translocations ... -
The stereological, immunohistological, and gene expression studies in an infected ischemic wound in diabetic rats treated by human adipose-derived stem cells and photobiomodulation
( Institute for Ionics , 2023 , Article)We investigated the impacts of photobiomodulation (PBM) and human allogeneic adipose-derived stem cells (ha-ADS) together and or alone applications on the stereological parameters, immunohistochemical characterizing of M1 ... -
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
( Elsevier , 2022 , Article)Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ... -
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
( Nature Publishing Group , 2016 , Article)STUDY DESIGN: Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ... -
The therapeutic potential of matcha tea: A critical review on human and animal studies
( Elsevier , 2023 , Article Review)Matcha is a powdered form of Japanese green tea that has been gaining global popularity recently. Matcha tea has various health benefits, including an enhancing effect on cognitive function, cardio-metabolic health, and ... -
Titanium Nanorods Loaded PCL Meshes with Enhanced Blood Vessel Formation and Cell Migration for Wound Dressing Applications.
( Wiley , 2019 , Article)Proper management of nonhealing wounds is an imperative clinical challenge. For the effective healing of chronic wounds, suitable wound coverage materials with the capability to accelerate cell migration, cell proliferation, ... -
Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential
( Elsevier , 2024 , Article)Plasticizers are considered as newly emerged contaminants. They are added to plastics to increase their flexibility and softness. Phthalate plasticizers including the Di-2-ethylhexyl phthalates (DEHP) are toxic and induce ... -
Toxicity evaluation of selected ionic liquid compounds on embryonic development of Zebrafish.
( Elsevier , 2018 , Article)Hydrate formation in seafloor pipelines is considered an economic and flow assurance issue for the oil and gas industries. Ionic liquids (ILs) have been recently used as potential hydrate inhibitors. Although branded as ... -
Toxoplasma infection and milk consumption: Meta-analysis of assumptions and evidences.
( Taylor & Francis , 2017 , Article)Toxoplasmosis is the most widespread infection worldwide. It occurs within congenital contamination, organ transplant or immune system depression. Primary infection is mainly foodborne with the ingestion of raw or undercooked ... -
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ... -
Translating advances in organ-on-a-chip technology for supporting organs
( John Wiley and Sons Inc. , 2019 , Article Review)Organ‐on‐a‐chip platforms have recently seen tremendous progress. They have found potential applications in the study of physiology and pathology of tissues, drug toxicity, and development of tissue models for replacement ... -
Transmissibility and Persistence of the Plasmid-Borne Mobile Colistin Resistance Gene, mcr-1, Harbored in Poultry-Associated E. coli
( MDPI , 2022 , Article)Colistin, a last-resort antibiotic, is used to treat infections caused by multi-drug-resistant Gram-negative bacteria. Colistin resistance can emerge by acquiring the mobile colistin gene, mcr-1, usually plasmid borne. ... -
Traumatic Brain Injury Can Affect Emotions and Behaviors
( Frontiers Media , 2023 , Article)Proper brain functioning is responsible for our feelings, behavior, and thinking. However, an injury to the brain can disrupt brain function, which can affect our emotions and behaviors. A traumatic brain injury (TBI) can ...