Browsing Biomedical Research Center by Title
Now showing items 509-528 of 709
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Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
( Dove Press , 2016 , Article)Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against ... -
Prevalence and genetic diversity of Blastocystis sp. among autochthonous and immigrant patients in Italy
( Elsevier , 2023 , Article)The prevalence of Blastocystis sp., its genetic diversity and the distribution of circulating subtypes (STs) were molecularly investigated in a cohort of autochthonous and immigrant patients with gastrointestinal symptoms ... -
Prevalence and molecular profiling of Epstein Barr virus (EBV) among healthy blood donors from different nationalities in Qatar.
( Public Library of Science , 2017 , Article)The Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis. EBV is highly prevalent lymphotropic herpesvirus and has been linked to several malignancies. Transmission is generally by oral secretions, ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ... -
Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar
( BioMed Central , 2016 , Article)Background Anelloviruses (TTV, TTMV, and TTMDV) have been associated with non A-G hepatitis. The goal of the current study was to estimate the prevalence of these anelloviruses in Qatar. Methods A total of 607 blood ... -
Prevalence of antibiotic resistant Escherichia coli isolates from fecal samples of food handlers in Qatar
( BioMed Central , 2018 , Article)Background: It is well documented that food handlers harbor and shed enteric foodborne pathogens causing foodborne disease outbreaks. However, little known on enteric antibiotic resistant (AR) bacteria carriage in ... -
Prevalence of antibiotic resistant Escherichia coli isolates from local and imported retail chicken carcasses.
( International Association for Food Protection , 2020 , Article)The spread of antibiotic resistance has been associated with consumption of food contaminated with pathogenic and non-pathogenic resistant bacteria. The objective of this study was to determine the prevalence of antibiotic ... -
Prevalence of Blastocystis sp. and other gastrointestinal pathogens among diarrheic COVID-19 patients in Italy
( Elsevier , 2024 , Article)BackgroundGastrointestinal pathogens (GPs) contribute significantly to the burden of illness worldwide with diarrhoea being the most common among gastrointestinal symptoms (GSs). In the COVID-19 disease, diarrhoea, could ... -
Prevalence of Gastrointestinal Protoz in Feral Cat Population in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Introduction: Doha city has a high feral cat population that is estimated to outnumber its human inhabitants by 2-3:1 with a total population of 2-3 million cats according to Qatar Cat Control Unit (QCCU). Doha had a ... -
Prevalence of hepatitis B and C viruses among migrant workers in Qatar.
( Springer Nature , 2024 , Article)Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ... -
The prevalence of HEV among non-A-C hepatitis in Qatar and efciency of serological markers for the diagnosis of hepatitis E
( BMC , 2021 , Article)Background: The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acute ... -
Prevalence of Virulence/Stress Genes in Campylobacter jejuni from Chicken Meat Sold in Qatari Retail Outlets
( Public Library of Science , 2016 , Article)Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Campylobacter spp. and the presence of five virulence genes (htrB, cdtB, clpP, cadF and ciaB) was assessed in isolates. Forty eight ... -
Production of Long-Acting CNGRC–CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment
( SAGE , 2021 , Article)Objectives: Aminopeptidase N (APN) is an enzyme highly expressed in metastatic cancers and could be used in targeted cancer therapy. Our previous work showed the successful construction of CNGRC–carboxypeptidase G2 (CPG2) ... -
Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses
( MDPI , 2021 , Article)Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared the effect of influenza types, A and B, and influenza shedding in patients’ stools on ... -
Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar
( MDPI , 2019 , Article)The present study is designed to compare demographic characteristics, plasma biochemistry, and the oral microbiome in obese (N = 37) and lean control (N = 36) subjects enrolled at Qatar Biobank, Qatar. Plasma hormones, ... -
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
( Nature Research , 2022 , Article)COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ... -
Protection against Reinfection with the Omicron BA.2.75 Subvariant
( Massachusetts Medical Society , 2023 , Other)The BA.2.75 sublineage of the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may escape neutralizing antibodies. The BA.2.75 sublineage (primarily the BA.2.75.2 subvariant) ... -
Protection against the omicron variant from previous SARS-CoV-2 infection
( Massachusetts Medical Society , 2022 , Other)Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits strong protection against reinfection with the B.1.1.7 (alpha),1,2 B.1.351 (beta),1 and B.1.617.2 (delta)3 variants. However, the ... -
Protection from previous natural infection compared with mRNA vaccination against SARS-CoV-2 infection and severe COVID-19 in Qatar: a retrospective cohort study
( Elsevier , 2022 , Article)BackgroundUnderstanding protection conferred by natural SARS-CoV-2 infection versus COVID-19 vaccination is important for informing vaccine mandate decisions. We compared protection conferred by natural infection versus ... -
Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage
( Nature Research , 2022 , Article)There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...