Browsing Biomedical Research Center by Title
Now showing items 608-627 of 708
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Smoking induced salivary microbiome dysbiosis and is correlated with lipid biomarkers
( Springer Nature , 2024 , Article)Background: The oral microbiome plays an essential role in maintaining oral homeostasis and health; smoking significantly affects it, leading to microbial dysbiosis. The study aims to investigate changes in the oral ... -
Snornas and mirnas networks underlying covid-19 disease severity
( MDPI , 2021 , Article)There is a lack of predictive markers for early and rapid identification of disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers ... -
Solar cultivation of microalgae in a desert environment for the development of techno-functional feed ingredients for aquaculture in Qatar
( Elsevier , 2022 , Article)The demand for aquaculture feed will increase in the coming years in order to ensure food security for a growing global population. Microalgae represent a potential fish-feed ingredient; however, the feasibility of their ... -
Soluble ACE2 and angiotensin II levels are modulated in hypertensive COVID-19 patients treated with different antihypertension drugs.
( Taylor and Francis , 2022 , Article)This study examines the effect of antihypertensive drugs on ACE2 and Angiotensin II levels in hypertensive COVID-19 patients. Hypertension is a common comorbidity among severe COVID-19 patients. ACE2 expression can be ... -
Soluble ACE2 and Angiotensin II levels Modulated in Hypertensive COVID-19 Patients treated with different Antihypertension Drugs
( Qatar University Press , 2021 , Poster)Hypertension is a major risk factor and common comorbidity among severe Coronavirus Disease 2019 (COVID-19) patients. Prominent antihypertensive drugs, such as angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin ... -
Special appreciations are given to top five peer-reviewers of journal of food quality and hazards control in 2018
( Shahid Sadoughi University of Medical Sciences , 2019 , Article)[No abstract available] -
Specific gene patterns and molecular pathways related to human carcinogenesis in different populations among various geographic locations.
( Wiley , 2016 , Other)We read with great interest the article by Beg et al,1 which was recently published in Cancer. Colorectal cancers (CRCs) are the most commonly diagnosed malignancies, accounting for approximately 1.36 million new cases ... -
The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review
( Mary Ann Liebert , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients’ adverse events and antimicrobial resistance (AMR) to the ... -
The Spectrum of Mutations of Homocystinuria in the MENA Region
( MDPI , 2020 , Article Review)Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ... -
Statistical methods and resources for biomarker discovery using metabolomics.
( BMC , 2023 , Article Review)Metabolomics is a dynamic tool for elucidating biochemical changes in human health and disease. Metabolic profiles provide a close insight into physiological states and are highly volatile to genetic and environmental ... -
Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells
( Elsevier , 2021 , Article)Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue engineering strategies focusing on biomaterial scaffolds incorporating cells and growth factors are emerging as highly promising ... -
Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension
( nature , 2021 , Article)Pulmonary arterial hypertension (PAH) is an incurable disease, although symptoms are treated with a range of dilator drugs. Despite their clinical benefits, these drugs are limited by systemic side-effects. It is, therefore, ... -
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
( Elsevier , 2021 , Article)HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ... -
Substantial toxic effect of water-pipe smoking on the early stage of embryonic development
( Oxford University Press , 2017 , Article)Water-pipe smoking (WPS) is the most widespread tobacco use in the Middle-East, and is rapidly spreading globally. Smoke from WP contains most of the compounds present in cigarette smoke, although in different proportions. ... -
Sulforaphane reduces obesity by reversing leptin resistance.
( eLife Sciences Publications , 2022 , Article)The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress ... -
Sulpiride Serves, a Substrate for the Gut Microbiome
( International Dose-Response Society , 2021 , Article)In the contemporary research world, the intestinal microbiome is now envisioned as a new body organ. Recently, the gut microbiome represents a new drug target in the gut, since various orthologues of intestinal drug ... -
Support of intelligent emergent materials to combat COVID-19 pandemic
( Springer , 2021 , Article)The COVID-19 pandemic, associated with SARS-CoV-2 infection transmitted via human to human and cause lifethreatening respiratory diseases, has emerged as an everincreasing global health and economic crisis since its ... -
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ... -
Synthesis and Optimization of a Highly Stable and Efficient BN/TiO2 Nanocomposite for Phenol Degradation: A Photocatalytic, Mechanistic and Environmental Impact Study
( Wiley , 2021 , Article)Different BN/TiO2 nanocomposites were prepared hydrothermally, and their ratio was optimized to get the best photocatalytic performance towards phenol degradation. They were characterized by x-ray photoelectron spectroscopy, ... -
Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications
( Dove Press , 2017 , Article)Herein, novel hybrid nanomaterials were developed for wound dressing applications with antimicrobial properties. Electrospinning was used to fabricate a double layer nanocomposite nanofibrous mat consisting of an upper ...