Browsing Biomedical Research Center by Publisher "Bentham Science Publishers"

Now showing items 1-7 of 7

    • Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. 

      Al-Jaber, Hend; Al-Muraikhy, Shamma; Jabr, Aldana Jabr; Yousuf, Aisha; Anwardeen, Najeha; ... more authors ( Bentham Science Publishers , 2024 , Article)
      Cell culture plays a crucial role in addressing fundamental research questions, particularly in studying insulin resistance (IR) mechanisms. Multiple in vitro models are utilized for this purpose, but their technical ...

    • Crosstalk between Microglia and Neurons in Neurotrauma: An Overview of the Underlying Mechanisms. 

      Haidar, Muhammad Ali; Ibeh, Stanley; Shakkour, Zaynab; Reslan, Mohammad Amine; Nwaiwu, Judith; ... more authors ( Bentham Science Publishers , 2022 , Article Review)
      Microglia are the resident immune cells of the brain and play a crucial role in housekeeping and maintaining homeostasis of the brain microenvironment. Upon injury or disease, microglial cells become activated, at least ...

    • The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer 

      Fatima, Kaneez; Mathew, Shilu; Faheem, Muhammed; Mehmood, Tahir; Yassine, Hadi Mohamad; ... more authors ( Bentham Science Publishers , 2018 , Article Review)
      The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...

    • Expression profile of MicroRNA: An Emerging Hallmark of Cancer. 

      Zaheer, Uzma; Faheem, Muhammed; Qadri, Ishtiaq; Begum, Nargis; Yassine, Hadi M; ... more authors ( Bentham Science Publishers , 2019 , Article Review)
      MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ...

    • Lipid-lowering therapies for atherosclerosis: Statins, fibrates, ezetimibe and pcsk9 monoclonal antibodies 

      Ali, A.H.; Younis, Nour; Abdallah, Rola; Shaer, Farah; Dakroub, Ali; ... more authors ( Bentham Science Publishers , 2021 , Article Review)
      Cardiovascular disease (CVD) remains the primary cause of global morbidity and mortality. CVD includes various life-threatening conditions such as myocardial infarction, stroke and peripheral arterial diseases. In this ...

    • Nanomedicine for Cancer. 

      Younis, Nour K; Yassine, Hadi M; Eid, Ali H ( Bentham Science Publishers , 2022 , Article)
      Over the past decades, oncology has occupied the lion’s share of all nanomedical applications [1-3]. In 2020, up to 65% of the clinical trials involving nanomaterials were attending to cancer therapeutics and diagnostics ...

    • Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers 

      Mahmoud, Alaa; Elkhalifa, Dana; Alali, Feras; Al Moustafa, Ala-Eddin; Khalil, Ashraf ( Bentham Science Publishers , 2020 , Article)
      Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...