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Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
(
Impact Journals
, 2018 , Article)
The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. ...
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin.
(
Elsevier
, 2019 , Article)
Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of pre-existing immunity and generation of new responses. To define the contribution of these two types of responses, we ...
Sarcoptes-World Molecular Network (Sarcoptes-WMN): integrating research on scabies.
(
Elsevier
, 2011 , Article)
Parasites threaten human and animal health globally. It is estimated that more than 60% of people on planet Earth carry at least one parasite, many of them several different species. Unfortunately, parasite studies suffer ...
Characterization of disturbed hemodynamics due to stenosed aortic jets with a Lagrangian Coherent structures technique
(
JAFM
, 2018 , Article)
Isfahan University of Technology. The aortic valve is located at left ventricular outlet and is exposed to the highest pressure in the cardiovascular system. Problems associated with the valve leaflet movement can cause ...
Qatar Biobank and Qatar Genome Programs Road Map
(
OMICS International
, 2015 , Article)
Qatar Biobank “QBB” is a large-scale, long term medical research initiative for the population of Qatar, which will serve as a platform and driver of biomedical research to achieve benefits for Qatar’s communities. Following ...
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
(
Elsevier
, 2017 , Article)
Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ...
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
(
Elsevier
, 2017 , Other)
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ...
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
(
Nature Research
, 2019 , Article)
Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ...
A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
(
Mary Ann Liebert
, 2017 , Article)
This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use ...
Drug release kinetics from a drug-eluting stent with asymmetrical coat
(
IMR Press Limited
, 2017 , Article)
The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ...