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Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
(
Bentham Science Publishers
, 2020 , Article)
Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...
Intercellular Communication in Cancer
(
Springer
, 2023 , Book chapter)
Junctional complexes play a central role in maintaining tissue hemostasis. The barrier function of epithelial cells, that maintain tissues coherence and coordination of cellular synchronicity, is a consequence of a junctional ...
Traumatic Brain Injury Can Affect Emotions and Behaviors
(
Frontiers Media
, 2023 , Article)
Proper brain functioning is responsible for our feelings, behavior, and thinking. However, an injury to the brain can disrupt brain function, which can affect our emotions and behaviors. A traumatic brain injury (TBI) can ...
Ultrasound controlled paclitaxel releasing system—A novel method for improving the availability of coronary artery drug coated balloon
(
Wiley
, 2020 , Article)
Objectives: The aim of this study is to improve local-drug delivery efficiency and tissue absorption using the ultrasound (US)-responsible drug coating based on a newly developed US-controlled paclitaxel release balloon. ...
Pandemic COVID-19 caused by SARS-CoV-2: genetic structure, vaccination, and therapeutic approaches
(
Springer
, 2021 , Article Review)
We give a summary of SARS-genetic CoV-2’s structure and evolution, as well as current attempts to develop efficient vaccine and treatment methods for SARS-CoV-2 infection, in this article. Most therapeutic strategies are ...
Protection against Reinfection with the Omicron BA.2.75 Subvariant
(
Massachusetts Medical Society
, 2023 , Other)
The BA.2.75 sublineage of the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may escape neutralizing antibodies. The BA.2.75 sublineage (primarily the BA.2.75.2 subvariant) ...
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
(
John Wiley and Sons Inc
, 2021 , Article)
Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ...
Cancer Metastasis: Dynamic Hetero-cellular Communications Between Cancer Cells and Host Tissues
(
Springer International Publishing
, 2023 , Book chapter)
Metastasis is the most devastating aspect of cancer. Originally, tumor cells arise from a single clone, and then they undergo additional mutations and acquire invasive and metastatic features. These acquired mutations are ...
PCovNet: A presymptomatic COVID-19 detection framework using deep learning model using wearables data
(
Elsevier
, 2022 , Article)
While the advanced diagnostic tools and healthcare management protocols have been struggling to contain the COVID-19 pandemic, the spread of the contagious viral pathogen before the symptom onset acted as the Achilles' ...
Nano-Engineering in Traumatic Brain Injury
(
Wiley
, 2023 , Book chapter)
Traumatic brain injury (TBI) is a leading cause of mortality and chronic disability worldwide TBI involves an initial primary phase triggered by an impactful force to the brain and a subsequent secondary pathological phase. ...