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Immunomodulation Induced by Host Pathogen Interaction
(
Hindawi
, 2019 , Article)
Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune ...
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
(
MDPI
, 2019 , Article)
For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...
Impact of Physical Exercise on Gut Microbiome, Inflammation, and the Pathobiology of Metabolic Disorders.
(
The Society for Biomedical
, 2019 , Article Review)
The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and energy homeostasis. ...
Molecular characterization of extended spectrum β -lactamases enterobacteriaceae causing lower urinary tract infection among pediatric population.
(
BioMed Central
, 2018 , Article)
The β-lactam antibiotics have traditionally been the main treatment of Enterobacteriaceae infections, nonetheless, the emergence of species producing β- Lactamases has rendered this class of antibiotics largely ineffective. ...
Antibiotic Resistance Profile of Commensal Escherichia coli Isolated from Broiler Chickens in Qatar.
(
International Association for Food Protection
, 2018 , Article)
Antibiotic resistance (AR) is a growing public health concern worldwide, and it is a top health challenge in the 21st century. AR among Enterobacteriaceae is rapidly increasing, especially in third-generation cephalosporins ...
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses
(
Elsevier Inc.
, 2016 , Article)
Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin ...
Improving Influenza Vaccination Rate among Primary Healthcare Workers in Qatar
(
MDPI
, 2017 , Article)
The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ...
Evolution and dynamics of the pandemic H1N1 influenza hemagglutinin protein from 2009 to 2017.
(
Springer Vienna
, 2018 , Article)
The emergence of swine-origin pandemic H1N1 (pH1N1) in 2009 invigorated extensive surveillance programs worldwide which have resulted in the deposition of large numbers of H1N1 sequences to Genbank. In the present study, ...
Pre-fusion structure of a human coronavirus spike protein
(
Nature Publishing Group
, 2015 , Article)
HKU1 is a human betacoronavirus that causes mild yet prevalent
respiratory disease1, and is related to the zoonotic SARS2 and
MERS3 betacoronaviruses, which have high fatality rates and
pandemic potential. Cell tropism ...
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
(
Nature Research
, 2021 , Article)
Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ...