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The QChip1 knowledgebase and microarray for precision medicine in Qatar
(
Nature Research
, 2022 , Article)
Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically population-private. The goal was to develop "QChip1," an inexpensive ...
A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
(
Mary Ann Liebert
, 2017 , Article)
This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use ...
High-risk human papillomaviruses and epstein–barr virus in colorectal cancer and their association with clinicopathological status
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ...
Internalization of metal-organic framework nanoparticles in human vascular cells: Implications for cardiovascular disease therapy
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Alteration of endothelial cells and the underlying vasculature plays a central role in the pathogenesis of various CVDs. The ...
Latest Developments in Adapting Deep Learning for Assessing TAVR Procedures and Outcomes
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Aortic valve defects are among the most prevalent clinical conditions. A severely damaged
or non-functioning aortic valve is commonly replaced with a bioprosthetic heart valve (BHV) via the
transcatheter aortic valve ...
Exercise Metabolome: Insights for Health and Performance
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Exercise has many benefits for physical and mental well-being. Metabolomics research has allowed scientists to study the impact of exercise on the body by analyzing metabolites released by tissues such as skeletal muscle, ...
Drug release kinetics from a drug-eluting stent with asymmetrical coat
(
IMR Press Limited
, 2017 , Article)
The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ...
Molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children
(
Frontiers Media S.A.
, 2017 , Article)
Pediatric diarrhea is a common cause of death among children under 5 years of age. In the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. Parasitic ...
The Effect of Chronic Endurance Exercise on Serum Levels of MOTS-c and Humanin in Professional Athletes
(
IMR Press Limited
, 2022 , Article)
Background: Humanin and the mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) are mitochondrial encoded peptides involved in energy metabolism, cytoprotection, longevity, insulin sensitivity and their expression ...
Medicago orbicularis Has Antioxidant, Antihemolytic, and Anti-cancerous Activities and Augments Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells
(
preprints
, 2023 , Article)
Cancer is the second leading cause of death, worldwide. Lung cancer is the leading cause of cancer-related mortality. Plant-based therapeutics and herbal medicine have played a vital role in the development of several ...