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Detection of Paracetamol as substrate of the gut microbiome
(
University of Karachi, Pharmacy College
, 2019 , Article)
Gut microbiome, a new organ; represent targets to alter pharmacokinetics of orally administered drugs. Recently, in vitro trials endorsed the idea that orally administered drugs interact and some of their quantity may be ...
Development of titanium dioxide nanowire incorporated poly(vinylidene fluoride–trifluoroethylene) scaffolds for bone tissue engineering applications
(
Springer New York LLC
, 2019 , Article)
Critical size bone defects that do not heal spontaneously are among the major reasons for the disability in majority of people with locomotor disabilities. Tissue engineering has become a promising approach for repairing ...
Immunomodulation Induced by Host Pathogen Interaction
(
Hindawi
, 2019 , Article)
Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune ...
Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells
(
Elsevier
, 2021 , Article)
Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue engineering strategies focusing on biomaterial scaffolds incorporating cells and growth factors are emerging as highly promising ...
Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients
(
MDPI
, 2021 , Article)
Antibiotic resistance is a growing public health problem globally, incurring health and cost
burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ...
Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
(
Springer
, 2019 , Article)
In this study, a set of polylactic acid (PLA)/polyphenol extracted from date palm fruit (DP) blends were prepared by electrospinning process to be used as cell culture scaffolds for tissue engineering applications. For ...
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
(
Qatar University Press
, 2021 , Poster)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ...
Patient Specific Transcatheter Aortic Valve Replacement Therapy Pathway with Computational Fluid Structure Interaction Analysis
(
Qatar University Press
, 2021 , Poster)
Total cardiovascular disease (CVD) prevalence has risen dramatically from 271 million in 1990 to 523 million in 2019, and CVD fatalities rose gradually from 12.1 million in 1990 to 18.6 million in 2019. According to American ...
Viral-Induced Enhanced Disease Illness
(
Frontiers Media
, 2018 , Article)
Understanding immune responses to viral infections is crucial to progress in the quest for effective infection prevention and control. The host immunity involves various mechanisms to combat viral infections. Under certain ...
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
(
MDPI
, 2019 , Article)
The use of chitosan nanoparticles (ChNPs) in various biological and environmental
applications is attracting great interest. However, potential side effects related to ChNP toxicity
remain the major limitation hampering ...