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Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.
(
American Society for Microbiology
, 2019 , Article)
Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ...
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
(
MDPI
, 2019 , Article)
Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to
the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO),
CMV infects people of all ages, and by ...
Biomechanical Investigation of Disturbed Hemodynamics-Induced Tissue Degeneration in Abdominal Aortic Aneurysms Using Computational and Experimental Techniques.
(
Frontiers Media
, 2019 , Article Review)
Abdominal aortic aneurysm (AAA) is the dilatation of the aorta beyond 50% of the normal vessel diameter. It is reported that 4-8% of men and 0.5-1% of women above 50 years of age bear an AAA and it accounts for ~15,000 ...
Comparative Phylogenetic and Residue Analysis of Hepatitis C Virus E1 Protein from the Middle East and North Africa Region
(
Kowsar (Research Center for Gastroenterology and Liver Diseases, Tehran, Iran)
, 2019 , Article)
Hepatitis C virus (HCV) is a major public health problem in the Middle East and North Africa (MENA) region with an estimate of over 15 million chronically infected patients. However, molecular characterization of circulating ...
Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells.
(
e-Century Publishing
, 2019 , Article)
Mesenchymal stem cells (MSCs) are undifferentiated cells that have the ability of self-renewal and trans-differentiation into other cell types. They hold out hope for finding a cure for many diseases. Nevertheless, there ...
Comparative Serological Study for the Prevalence of Anti-MERS Coronavirus Antibodies in High- and Low-Risk Groups in Qatar
(
Hindawi Publishing Corporation
, 2019 , Article)
Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) could be asymptomatic or cause mild influenza-like illness. Therefore, the prevalence of MERS-CoV infections in the general population could be ...
Gene expression and miRNAs profiling: Function and regulation in human epidermal growth factor receptor 2 (HER2) - positive breast cancer
(
MDPI AG
, 2019 , Article)
Breast cancer is the second most common cause of cancer-related deaths among women worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the subtypes, human epidermal growth factor receptor 2 ...
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
(
Nature Research
, 2019 , Article)
Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ...
Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar.
(
Public Library of Science
, 2019 , Article)
The World Health Organization WHO has estimated that in developed countries, up to 30% of the population may suffer from foodborne diseases each year, and that in developing countries up to 2 million deaths per annum can ...
Epidemiology of respiratory infections among adults in Qatar (2012-2017).
(
Public Library of Science
, 2019 , Article)
Limited data is available about the etiology of influenza like illnesses (ILIs) in Qatar. This study aimed at providing preliminary estimates of influenza and other respiratory infections circulating among adults in Qatar. ...