Biomedical Research Center: المرسلات الحديثة
السجلات المعروضة 781 -- 800 من 808
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First Study in Qatar to Reveal High Legionella Count in Cooling Towers
( Oxford University Press - ASCP , 2015 , Article)Legionella is an intracellular bacterium that can cause a severe communityacquired and nosocomial pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments, including manmade water ... -
Metagenomic analysis demonstrates the diversity of the fecal virome in asymptomatic pigs in East Africa
( Springer Vienna , 2016 , Article)Pigs harbor a variety of viruses that are closely related to human viruses and are suspected to have zoonotic potential. Little is known about the presence of viruses in smallholder farms where pigs are in close contact ... -
Is it the time for Hepatitis E virus (HEV) Testing for Blood Donors in Qatar?
( Qatar Foundation , 2016 , Conference)HEV is the etiologic agent of acute hepatitis E. Although HEV usually causes a self-limiting infection, the disease may develop into a chronic or fulminant form of Hepatitis. Sporadic HEV infections spread in several ... -
A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10
( Akadémiai Kiadó , 2015 , Article)L. pneumophila is an intracellular bacterium that replicates inside a membrane- bound vacuole called Legionella-containing vacuole (LCV), where it plentifully liberates its HtpB chaperonin. From LCV, HtpB reaches the ... -
Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing
( Future Medicine , 2016 , Article)Wound dressings play an important role in a patient’s recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ... -
PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals.
( Impact Journals , 2016 , Article)Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms ... -
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
( Bentham Science , 2016 , Book chapter)Alzheimer's disease (AD) is a complex neurodegenerative condition that is clinically characterized by impaired cognitive functions. The major morphologically observed lesion of AD encompasses the accumulation of extracellular ... -
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
( Future Medicine , 2015 , Article)Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ... -
Pre-fusion structure of a human coronavirus spike protein
( Nature Publishing Group , 2015 , Article)HKU1 is a human betacoronavirus that causes mild yet prevalent respiratory disease1, and is related to the zoonotic SARS2 and MERS3 betacoronaviruses, which have high fatality rates and pandemic potential. Cell tropism ... -
Common and Rare Genetic Variants Associated With Alzheimer's Disease
( WILEY PERIODICALS, INC. , 2016 , Article)Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ... -
Landscape of NAT2 polymorphisms among breast cancer.
( Elsevier Masson , 2016 , Article)PURPOSE: The prevalence of phenotypes of Arylamine N-acetyltransferase-2(NAT2) gene (i.e. fast, intermediate and slow acetylators) among ethnic groups, as well as the association studies regarding NAT2 polymorphisms and ... -
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
( Nature Publishing Group , 2016 , Article)STUDY DESIGN: Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ... -
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
( BioMed Central , 2016 , Article)Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely ... -
The Qatar Biobank: background and methods
( BioMed Central , 2015 , Article)Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ... -
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
( Wiley , 2015 , Article)Human Pegivirus (HPgV), formerly GB virus-C/ Hepatitis G virus (GBV-C/HGV), collectively known as GBV-C, is widely spread and has been reported to be associated with non-A–E hepatitis. To our knowledge, no previous ... -
Human microbiome and its association with health and diseases
( Wiley , 2016 , Article)Human microbiota are distinct communities of microorganisms that resides at different body niches. Exploration of the human microbiome has become a reality due to the availability of powerful metagenomics and metatranscriptomic ... -
Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
( Wiley , 2015 , Article)In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs) transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ... -
GOLD NANOPARTICLES-BASED ASSAYS FOR DIRECT AND COST EFFECTIVE DETECTION OF CLOSTRIDIUM DIFFICILE IN QATAR
(2015 , Master Thesis)Background Clostridium difficile Infection (CDI) is one of the common health problems worldwide. Prevention techniques require fast and precise detection with high sensitivity. Conventional diagnostic methods are ... -
The distribution of Blastocystis subtypes in isolates from Qatar
( BioMed Central Ltd. , 2015 , Article)Background: Blastocystis is a common single-celled intestinal parasite of humans and other animals comprising at least 17 genetically distinct small subunit ribosomal RNA lineages (subtypes (STs)), nine of which have been ... -
Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar
( BioMed Central Ltd. , 2014 , Article)Background: Human Papilloma Virus (HPV) infection is the major cause of cervical cancer worldwide. With limited data available on HPV prevalence in the Arab countries, this study aimed to identify the prevalence and ...
