Browsing Laboratory Animal Research Center by Subject "ADMET properties"
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Phytocompounds as potential inhibitors of p300-HIF1α interaction: A structure-based screening and molecular dynamics simulation analysis
( Society for Medicinal Plant and Natural Product Research (GA) - the Italian Society of Phytochemistry (SIF) , 2025 , Poster)Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1) [1]. For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ...