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The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons
(
Wiley
, 2023 , Article)
Photobiomodulation therapy (PBMT) is known as a complementary tool to alleviate pain sensation in patients, nevertheless, there is still a gap of knowledge on its mechanism of action, thus limiting its clinical employment. ...
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
(
Elsevier
, 2023 , Article)
Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ...
Epigenetic regulation of CXCR4 signaling in cancer pathogenesis and progression
(
Elsevier
, 2022 , Article)
Signaling involving chemokine receptor CXCR4 and its ligand SDF-1/CXL12 has been investigated for many years for its possible role in cancer progression and pathogenesis. Evidence emerging from clinical studies in recent ...
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
(
Elsevier
, 2021 , Article)
Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. The high mortality associated with this malignancy indicates ...
Changes in resting-state functional brain activity are associated with waning cognitive functions in HIV-infected children.
(
Elsevier
, 2018 , Article)
Delayed brain development in perinatally HIV-infected children may affect the functional brain activity and subsequently cognitive function. The current study evaluated the functional brain activity in HIV-infected children ...
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance.
(
Springer Verlag
, 2019 , Article)
The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor ...
Gut Microbiota Dysbiosis in Cafeteria Diet Fed Sprague Dawley Rats
(
Scientific Research Publishing
, 2018 , Article)
Diet plays a major role in the body physiology and metabolism. The quantity,
nature and stability of the macronutrients present in the diet have a major impact on the composition of gut microbiota. Gut microbiota plays a ...
A loss-of-function NCSTN mutation associated with familial Dowling Degos disease and hidradenitis suppurativa
(
Wiley
, 2023 , Article)
Dowling Degos disease (DDD) is a rare autosomal dominant genodermatosis characterized by acquired, slowly progressive reticulated pigmented lesions primarily involving flexural skin areas. Mutations in KRT5, POGLUT-1 and ...
SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle
(
Wiley
, 2017 , Article)
Silent mating type information regulation 2 homologue 1 (SIRT1) activity and content increased significantly in overload-induced hypertrophy. SIRT1-mediated signalling through Akt, the endothelial nitric oxide synthase ...
NF-κB Essential MOdulator (NEMO) Is Critical for Thyroid Function
(
American Society for Biochemistry and Molecular Biology
, 2016 , Article)
The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis ...