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Now showing items 31-40 of 82
Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.
(
MDPI
, 2020 , Article Review)
Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly recognized as both a disorder of mental health and social burden, but also as an anxiety disorder characterized by fear, stress, and ...
Cardiac Myosin Binding Protein-C in Sprague Dawley (SD) Rats exposed to Sub-Chronic oral dose of Cadmium Chloride
(
Qatar University Press
, 2021 , Poster)
Cadmium is one of the major environmental pollutants associated with an increment in industrial and urbanization activities. It has health consequences when it reaches the human diet through the soil, water, and plant. ...
Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells.
(
BMC
, 2021 , Article Review)
Protein ubiquitination is one of the most crucial posttranslational modifications responsible for regulating the stability and activity of proteins involved in homeostatic cellular function. Inconsistencies in the ...
Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury
(
Scientific Research Publishing
, 2019 , Article Review)
Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...
Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy.
(
Springer Nature
, 2021 , Article Review)
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have revealed the highly heterogeneous and ...
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
(
Springer Nature
, 2021 , Article Review)
Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. ...
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
(
BMC
, 2021 , Article Review)
Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...
Role of NAD+ in regulating cellular and metabolic signaling pathways
(
Elsevier
, 2021 , Article Review)
BackgroundNicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD+ is often ...
miRNAs as novel immunoregulators in cancer
(
Elsevier
, 2021 , Article Review)
The immune system is a well-known vital regulator of tumor growth, and one of the main hallmarks of cancer is evading the immune system. Immune system deregulation can lead to immune surveillance evasion, sustained cancer ...
Chemokine-cytokine networks in the head and neck tumor microenvironment
(
MDPI
, 2021 , Article Review)
Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a dismal patient prognosis. Despite significant advances in treatment modalities, the five-year survival rate in patients with HNSCC has improved ...