Browsing by Author "MRAICHE, FATIMA"
Now showing items 1-20 of 50
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Algae-derived bioactive compounds with anti-lung cancer potential
( MDPI , 2020 , Article Review)Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of ... -
An Examination of the Employment Preparedness, Job Satisfaction, and Impact in the Workplace of Qatar University Pharmacy Alumni: A Mixed Methods Study
( Qatar University Press , 2021 , Poster)Introduction: The level of alumni's job satisfaction and preparedness has been found to affect the impact in the workplace. Little is known about alumni's employment experience in Qatar. Objective: The aim of this study ... -
Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
( Elsevier , 2020 , Article)Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ... -
Anticancer potential of sanguinarine for various human malignancies
( Future Medicine Ltd. , 2017 , Article Review)Sanguinarine (Sang) - a benzophenanthridine alkaloid extracted from Sanguinaria canadensis - exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory activities on tumor cells of various cancer types as ... -
Asterarcys quadricellulare (Chlorophyceae) protects H9c2 cardiomyoblasts from H2O2-induced oxidative stress
( Springer , 2022 , Article)Oxidative stress has recently been identified as an important mediator of cardiovascular diseases. The need to find efficient antioxidant molecules is essential in the disease’s prevention. Therefore, the present study ... -
Biotechnology content in pharmacy curricula: Focus on Arab Countries
( Elsevier , 2023 , Article)Introduction: Pharmaceutical biotechnology involves using the principles of biotechnology to develop drugs. With the rapid increase in biopharmaceutical products being developed and approved for use, educating pharmacy ... -
Cathepsin B Induced Cardiomyocyte Hypertrophy Requires Activation of The Na+/H+ Exchanger Isoform-1
(2016 , Master Thesis)Multiple studies have demonstrated that proteases, specifically cathepsin B (Cat B) and matrix metalloproteinase-9 (MMP-9) contribute to the remodeling of the extracellular matrix (ECM), a hallmark of cardiac hypertrophy ... -
The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
(2014 , Master Thesis)The Na+/H+ exchanger-1 (NHE1) is a ubiquitously expressed housekeeping glycoprotein that functions to regulate intracellular pH. Enhanced expression/activity of NHE1 has been implicated in cardiac hypertrophy (CH). Recently, ... -
Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery
( Royal Society of Chemistry , 2022 , Article)Developing novel nanocarriers for anticancer drug delivery has become a ‘promising niche’. The toxicity of the carrier and its efficacy in treatment modalities have become cardinal points as they can impede the progress ... -
Correction to: Developing Leadership Skills in Pharmacy Education
( Springer Nature , 2023 , Article)The article “Developing Leadership Skills in Pharmacy Education” was originally published electronically on the publisher’s internet portal on 22 March 2022 with an error in the author group. The family name of the third ... -
Corrigendum: Curcumin-mediated degradation of S-phase kinase protein 2 induces cytotoxic effects in human papillomavirus-positive and negative squamous carcinoma cells(Front. Oncol., (2018), 8, (399), 10.3389/fonc.2018.00399)
( Frontiers Media SA , 2023 , Article)In the published article, there was an error in the Funding statement. The grant number included was incorrect. The original text incorrectly states that "This work was supported by Medical Research Centre (Grant No. RP # ... -
Crosstalk between Sodium–Glucose Cotransporter Inhibitors and Sodium–Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases
( MDPI , 2021 , Article)Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of ... -
The design and implementation of an undergraduate health professional degree elective course on scientific writing, peer assessment, and critical appraisal
( Elsevier , 2022 , Other)Background and purpose: Strong writing skills are critical to the pharmacy profession. This paper describes the design, delivery, and impact of a course intended to develop pharmacy students' scientific writing, peer ... -
Developing Leadership Skills in Pharmacy Education
( Springer , 2022 , Article)Leadership could refer to holding official leadership positions or advocating for patients and the profession. Different pharmacy organizations recommend the inclusion of leadership development in pharmacy education and ... -
Editorial: Recent advancements in neoadjuvant chemotherapy for specific breast cancer subtypes
( Frontiers Media S.A. , 2022 , Article)Most locally advanced breast cancer patients undergo pre-surgery treatment known as neoadjuvant chemotherapy (NAC). The purpose of NAC is to reduce the tumor’s size and improve surgical outcomes, cosmetic results, and ... -
Effect of CYP2C19 genetic variants on bleeding and major adverse cardiovascular events in a cohort of Arab patients undergoing percutaneous coronary intervention and stent implantation
( Lippincott Williams and Wilkins , 2022 , Article)Introduction One-third of patients have clopidogrel resistance that may lead to major adverse cardiac events (MACEs). By contrast, it was found that some clopidogrel-treated patients have hyperresponsive platelets that are ... -
THE EFFECT OF GENETIC AND NON-GENETIC FACTORS ON WARFARIN DOSE VARIABILITY IN QATARI POPULATION
(2018 , Master Thesis)Introduction: Genetic and non-genetic factors were shown to affect warfarin dosing; however, their effect may vary from one population to the other. No previous studies were conducted on the Qatari population to elucidate ... -
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
( Pharmacogenomics Journal , 2020 , Article)The objective of this study is to estimate the prevalence of VKORC1, CYP2C9, and CYP4F2 genetic variants and their contribution to warfarin dose variability in Qataris. One hundred and fifty warfarin-treated Qatari patients ... -
The Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced Cardiotoxicity
( OMICS International , 2015 , Article)Background: Doxorubicin (DOX), a widely used anticancer drug, has been associated with cardiotoxicity. Recently, DOX-induced cardiotoxicity has been attributed to topoisomerase II (TOPII)-β expression and activity. In our ... -
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
( Springer , 2022 , Article)Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ...
