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المؤلفKhan, Iftikhar
المؤلفYousaf, Sakib
المؤلفAlhnan, Mohamed Albed
المؤلفAhmed, Waqar
المؤلفElhissi, Abdelbary
المؤلفJackson, Mark J.
تاريخ الإتاحة2021-09-07T06:16:22Z
تاريخ النشر2016
اسم المنشورSurgical Tools and Medical Devices, Second Edition
المصدرScopus
معرّف المصادر الموحدhttp://dx.doi.org/10.1007/978-3-319-33489-9_19
معرّف المصادر الموحدhttp://hdl.handle.net/10576/22833
الملخصFor the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. Since the nineteenth century, many devices have been designed to deliver drugs but the modern era started from 1956 with the introduction of the first metered dose inhaler. These devices can generate aerosols with uniform size distribution, resulting in high deposition in the deep lung which has high surface area (100 m2). Devices that have been commonly used for pulmonary drug delivery are pressurized metered dose inhalers (pMDIs), dry powder inhalers (DPIs) and nebulizers. This review introduces and evaluates the applications of devices used in inhalation therapy and the influence of design characteristics on the delivery of medical aerosols. Springer International Publishing Switzerland 2007, 2016.
اللغةen
الناشرSpringer International Publishing
الموضوعAsthma
Drug delivery
Inhaler
Nebulizer
Pulmonary
العنوانDesign characteristics of inhaler devices used for pulmonary delivery of medical aerosols
النوعBook chapter
الصفحات573-592
dc.accessType Abstract Only


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عرض بسيط للتسجيلة