Browsing Pharmacy Research by Title
Now showing items 1-20 of 1318
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5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism
( Springer Verlag , 2016 , Article)Recent studies have established the role of mid-chain hydroxyeicosatetraenoic acids (HETEs) in the development of cardiovascular disease. Mid-chain HETEs have been reported to have vasoconstrictive and pro-inflammatory ... -
5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism
( Springer Verlag , 2016 , Article)Recent studies have established the role of mid-chain hydroxyeicosatetraenoic acids (HETEs) in the development of cardiovascular disease. Mid-chain HETEs have been reported to have vasoconstrictive and pro-inflammatory ... -
6-Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation
( American Chemical Society (ACS) , 2023 , Article)Patients with sepsis are at a high risk of morbidity and mortality due to multiple organ injuries caused by pathological inflammation. Although sepsis is accompanied by multiple organ injuries, acute renal injury is a ... -
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
( MDPI AG , 2019 , Article)Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ... -
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
( Springer Science and Business Media Deutschland GmbH , 2022 , Article)Background: Sodium glucose co-transporter 2 inhibitors (SGLT2is) are a novel class of oral antidiabetic drugs. To date, there are no pharmacoepidemiologic studies investigating the pattern of use of SGLT2is compared to ... -
A case of probable esomeprazole-induced transient liver injury in a pregnant woman with hyperemesis
( Dove Medical Press Ltd , 2016 , Article)We report a case of 22-year-old primigravida presented to Women's Hospital - Hamad Medical Corporation emergency with severe epigastric pain, nausea, and vomiting. On admission, she was dehydrated with remarkably worsening ... -
A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain
(2013 , Article)A 46-year-old female patient developed severe abdominal pain shortly after taking levofloxacin, 1000. mg for acute bacterial sinusitis. The pain started after taking the first dose of levofloxacin and became worse after ... -
A Comparative Approach to Screen the Capability of Raman and Infrared (Mid- and Near-) Spectroscopy for Quantification of Low-Active Pharmaceutical Ingredient Content Solid Dosage Forms: The Case of Alprazolam
( SAGE Publications Inc. , 2020 , Article)Content uniformity is a critical attribute for potent and low-dosage formulations of active pharmaceutical ingredient (API) that, in addition to the formulation parameters, plays pivotal role during pharmaceutical development ... -
A comprehensive production method of self-cryoprotected nano-liposome powders
( Elsevier , 2015 , Article)This study provided a convenient approach for large scale production of hydrogenated soya phosphatidylcholine nano-liposome powders using beclometasone dipropionate as a model drug and sucrose as proliposome carrier. ... -
A comprehensive review on the antiviral activities of chalcones
( Taylor and Francis Ltd. , 2021 , Article)Some viral outbreaks have plagued the world since antiquity, including the most recent COVID-19 pandemic. The continuous spread and emergence of new viral diseases have urged the discovery of novel treatment options that ... -
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
( John Wiley and Sons Inc , 2021 , Article)Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ... -
A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice
( Elsevier Inc. , 2018 , Article Review)Introduction: Pharmacists are key professionals in the collaborative working process and are integral members of the healthcare team. However, there is paucity of information regarding their perspectives towards interprofessional ... -
A cost-effectiveness analysis for high versus standard (low) dose caffeine for the treatment of apnea in neonatal intensive care unit
( Taylor and Francis Ltd. , 2024 , Article)Objective: Preterm babies are prone to experiencing apnea of prematurity (AOP), mostly characterised by a pause in breathing lasting a minimum of 20 seconds. Recent literature supported higher maintenance doses of caffeine, ... -
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
( Springer International Publishing , 2016 , Article Review)Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ... -
A Cross-Sectional Study of Vaccination-Related Education in Pharmacy Programs in the Middle East
( Elsevier , 2024 , Article)Objective: Pharmacists play pivotal roles in improving vaccination rates. However, absence of vaccination-related undergraduate education impedes their ability for these roles. The study aims were to scope vaccination-related ... -
A holistic conceptual framework model to describe medication adherence in and guide interventions in diabetes mellitus
( Elsevier Inc. , 2018 , Article)BACKGROUND: Nonadherence to medications in patients with diabetes, which results in poor treatment outcomes and increased healthcare costs, is commonly reported globally. Factors associated with medication adherence have ... -
A literature-based algorithm for the assessment, management, and monitoring of drug-induced QTc prolongation in the psychiatric population
( Dove Medical Press Ltd. , 2019 , Article Review)Background: Certain psychotropics and a number of other medications used to treat medical conditions in psychiatric patients can increase the risk of prolonging the corrected QT (QTc) interval on the electrocardiogram, ... -
A message from the new Editor-in-Chief
( Springer Science and Business Media Deutschland GmbH , 2021 , Article)[No abstract available] -
A new experimental community pharmacy internship module for undergraduate pharmacy students in western Nepal: overview and reflections
(2017 , Article)Community pharmacies in Nepal and other South Asian countries are in a mediocre state due to poor regulation and the fact that many pharmacies are run by people with insufficient training in dispensing. This has led to the ... -
A pharmacist-delivered smoking cessation program in Qatar: an exploration of pharmacists' and patients' perspectives of the program
( Springer Science and Business Media Deutschland GmbH , 2021 , Article)Background Tobacco use is one of the major causes of morbidity and mortality. An intensive pharmacist-delivered smoking cessation program was implemented in eight primary care pharmacies in Qatar. Objective This study aimed ...
