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AuthorMousnad, M. A.
AuthorShafie, A. A.
AuthorIbrahim, Mohamed Izham Mohamed
Available date2022-04-10T10:25:35Z
Publication Date2014
Publication NameHealth Policy
ResourceScopus
URIhttp://hdl.handle.net/10576/29431
URIhttp://dx.doi.org/10.1016/j.healthpol.2014.03.010
AbstractObjective: To systematically identify the main factors contributing to the increase in pharmaceutical expenditures. Methods: A systematic search of published studies was conducted utilising major widely used electronic databases using the search terms 'factors,' 'financing,' 'pharmaceutical,' and 'expenditures.' To be included, the studies needed to: (1) measure at least one of the following outcomes: total growth in pharmaceutical expenditures, price growth or quantity growth; (2) mention a clear method for analysing the impact of factors affecting the increases in drug expenditures; (3) be written in English. Nonprimary articles that were published only as an abstract, a review, a commentary or a letter were excluded. Main results: From a total of 2039 studies, only 25 were included in the full review. The main determinant categories that were identified in the review were factors related to price, utilisation, therapeutic choice, demand and health care system. Conclusions: The major cost drivers were found to be changes in drug quantities and therapies as well as new drugs. It is important for policymakers to understand pharmaceutical spending trends and the factors that influence them in order to formulate effective cost containment strategies and design optimum drug policy.
Languageen
PublisherElsevier Ireland Ltd
SubjectDrug financing
Drug quantities changes
Drug therapies changes
New drugs
Pharmaceutical expenditures
Spending determinants
TitleSystematic review of factors affecting pharmaceutical expenditures
TypeArticle Review
Pagination137-146
Issue Number3-Feb
Volume Number116
dc.accessType Abstract Only


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