Reference ranges of lymphocyte subsets in healthy Qatari adults
المؤلف | Al-Thani, Asma |
المؤلف | Saleem, Wedad H |
المؤلف | Al-Marwani, Asma |
المؤلف | Alnaqdy, Adel |
المؤلف | Sharafeldin, Hend |
تاريخ الإتاحة | 2015-10-29T05:40:29Z |
تاريخ النشر | 2015-09 |
اسم المنشور | Biomarkers in Medicine |
الرقم المعياري الدولي للكتاب | 1752-0363 |
الرقم المعياري الدولي للكتاب | 1752-0371 (online) |
الملخص | Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. Patients & Methods: Blood samples (n = 150) were investigated using four colors flow cytometery. Results: The mean percentage and absolute values of the lymphocyte subsets were: CD3: 73.6 ± 6.1%; 2,072 ± 644 cells/μl; CD4: 41.1 ± 7.9%; 1,167 ± 396 cells/ μl; CD8: 33.8 ± 7.1%; 967 ± 364 cells/μl; B cells (CD19+): 11.3 ± 3.9%; 318 ± 144 cells/μl and natural killer (NK) cells (CD16/56+): 16.5 ± 6.3%, 440 ± 401 cells/μl, respectively. The CD4/CD8 ratio was 1.3 ± 0.5. The ratio, CD3+ and CD4+ percentage and CD4+ cell counts were significantly higher in females; CD8+ and NK cell count and CD8+ percentage were significantly higher in males. The impact of age was less certain. Conclusion: The reference values of lymphocyte subsets appear to be specific to this population, demonstrating the importance of establishing local reference ranges. |
اللغة | en |
الناشر | Future Medicine Ltd |
الموضوع | B cells CD3 CD4 CD8 flow cytometry lymphocyte subsets natural killer cells reference ranges |
النوع | Article |
الصفحات | 443-452 |
رقم العدد | 5 |
رقم المجلد | 9 |
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