Reference ranges of lymphocyte subsets in healthy Qatari adults
Author | Al-Thani, Asma |
Author | Saleem, Wedad H |
Author | Al-Marwani, Asma |
Author | Alnaqdy, Adel |
Author | Sharafeldin, Hend |
Available date | 2015-10-29T05:40:29Z |
Publication Date | 2015-09 |
Publication Name | Biomarkers in Medicine |
ISSN | 1752-0363 |
ISSN | 1752-0371 (online) |
Abstract | Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. Patients & Methods: Blood samples (n = 150) were investigated using four colors flow cytometery. Results: The mean percentage and absolute values of the lymphocyte subsets were: CD3: 73.6 ± 6.1%; 2,072 ± 644 cells/μl; CD4: 41.1 ± 7.9%; 1,167 ± 396 cells/ μl; CD8: 33.8 ± 7.1%; 967 ± 364 cells/μl; B cells (CD19+): 11.3 ± 3.9%; 318 ± 144 cells/μl and natural killer (NK) cells (CD16/56+): 16.5 ± 6.3%, 440 ± 401 cells/μl, respectively. The CD4/CD8 ratio was 1.3 ± 0.5. The ratio, CD3+ and CD4+ percentage and CD4+ cell counts were significantly higher in females; CD8+ and NK cell count and CD8+ percentage were significantly higher in males. The impact of age was less certain. Conclusion: The reference values of lymphocyte subsets appear to be specific to this population, demonstrating the importance of establishing local reference ranges. |
Language | en |
Publisher | Future Medicine Ltd |
Subject | B cells CD3 CD4 CD8 flow cytometry lymphocyte subsets natural killer cells reference ranges |
Type | Article |
Pagination | 443-452 |
Issue Number | 5 |
Volume Number | 9 |
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Biomedical Research Center Research [709 items ]
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Health Sciences-CAS (pre 2016) [141 items ]