Immune Imprinting and Protection against Repeat Reinfection with SARS-CoV-2
| Author | Chemaitelly, Hiam |
| Author | Ayoub, Houssein H. |
| Author | Tang, Patrick |
| Author | Hasan, Mohammad R. |
| Author | Coyle, Peter |
| Author | Yassine, Hadi M. |
| Author | Al-Khatib, Hebah A. |
| Author | Smatti, Maria K. |
| Author | Al-Kanaani, Zaina |
| Author | Al-Kuwari, Einas |
| Author | Jeremijenko, Andrew |
| Author | Kaleeckal, Anvar H. |
| Author | Latif, Ali N. |
| Author | Shaik, Riyazuddin M. |
| Author | Abdul-Rahim, Hanan F. |
| Author | Nasrallah, Gheyath K. |
| Author | Al-Kuwari, Mohamed G. |
| Author | Butt, Adeel A. |
| Author | Al-Romaihi, Hamad E. |
| Author | Al-Thani, Mohamed H. |
| Author | Al-Khal, Abdullatif |
| Author | Bertollini, Roberto |
| Author | Abu-Raddad, Laith J. |
| Available date | 2022-12-25T07:34:37Z |
| Publication Date | 2022-11-03 |
| Publication Name | New England Journal of Medicine |
| Identifier | http://dx.doi.org/10.1056/NEJMc2211055 |
| Citation | Chemaitelly H, Ayoub HH, Tang P, et al. Immune Imprinting and Protection against Repeat Reinfection with SARS-CoV-2. N Engl J Med. 2022;387(18):1716-1718. doi:10.1056/NEJMc2211055 |
| ISSN | 00284793 |
| Abstract | More than 2 years into the coronavirus disease 2019 (Covid-19) pandemic, the global population carries heterogeneous immune histories derived from various exposures to infection, viral variants, and vaccination.1 Evidence at the level of binding and neutralizing antibodies and B-cell and T-cell immunity suggests that a history of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can have a negative effect on subsequent protective immunity.1 In particular, the immune response to B.1.1.529 (omicron) subvariants could be compromised by differential immune imprinting in persons who have had a previous infection with the original virus or the B.1.1.7 (alpha) variant.1 |
| Language | en |
| Publisher | Massachusetts Medical Society |
| Subject | SARS-CoV-2 Immune Imprinting COVID-19 |
| Type | Other |
| Issue Number | 18 |
| Volume Number | 387 |
| ESSN | 1533-4406 |
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COVID-19 Research [789 items ]