Biomedical Sciences
Recent Submissions
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Development of an RT-LAMP Assay for Detecting tet(M) in Enterococcus Species: Enhancing AMR Surveillance Within the One Health Sectors
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)The increasing prevalence of antimicrobial-resistant (AMR) bacteria in humans, animals, and the environment underscores the necessity for a rapid, sensitive, and specific method to identify resistance genes. Objectives: ... -
Silicone quaterium-22 surfactant as an eco-friendly carbon steel anticorrosive: Assessment of corrosion inhibition properties and ecotoxicity in zebrafish embryos
( Elsevier , 2025 , Article)Corrosion of carbon steel pipelines in the oil and gas industry presents operational and environmental challenges, requiring safer alternatives to toxic corrosion inhibitors. This study evaluates Silicon-Q-22 (SQ22) as a ... -
Comprehensive global-scale evaluation of the COVID-19 pandemic associated with 234 countries, territories, and sub-national locations during 2020–2024
( Springer Nature , 2025 , Article)Comprehensive estimation of COVID-19, including infection, death, excess mortality, case fatality rate (CFR), and infection fatality rate (IFR), is essential for understanding the pandemic’s pattern. The location-specific ... -
Correction to: Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels (Emergent Materials, (2025), 8, 2, (985-998), 10.1007/s42247-024-00888-7)
( Springer Nature , 2025 , Article)The original version of this publication contained wrong texts in the Acknowledgement section and in the Author contributions section. In addition, the article note on page 1 has been corrected. These errors have been ... -
Comprehensive performance evaluation of four chemiluminescence immunoassays for detecting vitamin D deficiency across diverse clinical conditions
( The Public Library of Science (PLOS) , 2025 , Article)Background/Objectives Vitamin D deficiency is a significant global health concern, requiring accurate diagnosis. This study evaluates the performance of four chemiluminescent immunoassay (CLIA) platforms; Snibe, Roche, ... -
Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials
( Elsevier , 2025 , Article)BackgroundSurgical site infections (SSIs) are a major cause of postoperative complications, increasing morbidity and healthcare costs. Silver-based dressings are commonly used due to their antimicrobial properties, but ... -
Outcomes and management of Peyronie’s disease with combined treatment of collagenase clostridium histolyticum, vacuum erection device, and tadalafil
( Wolters Kluwer Medknow Publications , 2025 , Article)Peyronie’s disease (PD) is a connective tissue disorder characterized by abnormal collagen deposition in the tunica albuginea, leading to penile curvature, pain, and erectile dysfunction. This study aimed to evaluate the ... -
Exploring Differentially Methylated Genes among Preterm Birth and Full-Term Birth
( Karger , 2025 , Article)INTRODUCTION: Preterm birth (PTB) is a major contributor to neonatal morbidity and mortality. DNA methylation plays a critical role in fetal development and may serve as an epigenetic biomarker for PTB. However, few ... -
Characterizing low femoral neck BMD in Qatar Biobank participants using machine learning models
( Springer Nature , 2025 , Article)Background: Identifying determinants of low bone mineral density (BMD) is crucial for understanding the underlying pathobiology and developing effective prevention and management strategies. Here we applied machine learning ... -
Near-complete Middle Eastern genomes refine autozygosity and enhance disease-causing and population-specific variant discovery
( Elsevier , 2025 , Article)Advances in long-read sequencing have enabled routine complete assembly of human genomes, but much remains to be done to represent broader populations and show impact on disease-gene discovery. Here, we report highly ... -
Diet-induced mechanical stress promotes immune and metabolic alterations in the Drosophila melanogaster digestive tract
( Elsevier , 2025 , Article)A fundamental query in immunology is how cells recognize danger in the tissue milieu. For many years, standpoints were mainly centered around damaged cells or structures of invading pathogens, like lipopolysaccharide, being ... -
The role of soluble CD40L in autoimmune diseases
( Elsevier , 2025 , Article)CD40−CD40L is essential for immune system modulation because it coordinates both adaptive and inflammatory responses.Systemic lupus erythematosus, multiple sclerosis, inflammatory bowel disease, thrombocytopenic purpura, ... -
Comprehensive analysis of human coronavirus antibody responses in ICU and non-ICU COVID-19 patients reveals IgG3 against SARS-CoV-2 spike protein as a key biomarker of disease severity
( Microbiology Society , 2025 , Article)Introduction. Pre-existing immunity to human coronaviruses (HCoVs) may shape the immune response in COVID-19 patients. Increasing evidence suggests that immune cross-reactivity between SARS-CoV-2 and other coronaviruses ... -
Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination
( Taylor and Francis Group , 2025 , Article)This study characterized antibody-dependent enhancement (ADE) in serum samples from individuals exposed to SARS-CoV-2 via infection or vaccination and evaluated its association with SARS-CoV-2 variants (Wuhan and Omicron), ... -
The impact of pre-existing immunity on the emergence of within-host immune-escape mutations in Omicron lineages
( Microbiology Society , 2025 , Article)The Omicron variant of SARS-CoV-2 circulating amongst highly immunized populations is anticipated to induce immunological pressures, potentially compromising existing immunity. This study investigates vaccine-induced ... -
Glucosamine Schiff bases as fluorescent sensors for recognition of Al+3 and Zn+2 ions
( Elsevier , 2025 , Article)Glucosamine salicylidene (GAS) and Glucosamine-4-nitrosalicylidene (GANS) were synthesized using microwave and investigated as water-soluble chemosensors for aluminum and zinc ions. UV–vis, fluorescence titration, binding ... -
Reactive Oxygen Species: From Tumorigenesis to Therapeutic Strategies in Cancer
( John Wiley & Sons , 2025 , Article)Background: Reactive oxygen species (ROS), a class of highly reactive molecules, are closely linked to the pathogenesis of various cancers. While ROS primarily originate from normal cellular processes, external stimuli can ... -
Current epidemiological status of mosquito-borne arboviruses in Gulf countries: a systematic review and meta-analysis
( Springer Nature , 2025 , Article)Background: Mosquito-borne viral (MBV) infections caused by dengue virus (DENV), Rift Valley fever virus (RVFV), West Nile virus (WNV), and chikungunya virus (CHIKV) pose a significant global public health concern. The aim ... -
Role of Exosome in Solid Cancer Progression and Its Potential Therapeutics in Cancer Treatment
( John Wiley & Sons , 2025 , Article)Background: Exosomes are extracellular vesicles ranging from 40 to 100 nm in diameter that mediate intercellular communication by transferring proteins, lipids, nucleic acids, and other metabolites. In the context of cancer, ... -
Cardio-Rheumatic Diseases: Inflammasomes Behaving Badly
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Cardio-rheumatology is an evolving and interdisciplinary field lying at the intersection of rheumatology and cardiovascular medicine that recognizes that individuals with autoimmune and inflammatory rheumatic complications ...
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