College of Medicine: Recent submissions
Now showing items 181-200 of 1457
-
Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials.
( Springer Nature , 2024 , Article)Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recognized. We aimed ... -
Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways.
( Springer Nature , 2024 , Article)Recent investigations have reported the benefits of using a tyrosine kinase inhibitor, dasatinib (DA), as well as programmed death-ligand 1 (PD-L1) inhibitors in the management of several solid tumors, including breast ... -
Correction: Statistical analysis plan and protocol updates for Gestational diabetes in Uganda and India: Design and Evaluation of Educational Films for Improving Screening and Self-management (GUIDES) trial.
( BioMed Central (BMC) , 2024 , Article)Following publication of the original article [1], we have been notified that the 5th author’s affiliation was incorrect. Corrected affiliation: Giridhara R Babu, Professor of Global Health, Department of Population ... -
Prenatal psychological distress and 11β-HSD2 gene expression in human placentas: Systematic review and meta-analysis
( Elsevier , 2024 , Article Review)BackgroundThe placenta acts as a buffer to regulate the degree of fetal exposure to maternal cortisol through the 11-Beta Hydroxysteroid Dehydrogenase isoenzyme type 2 (11-β HSD2) enzyme. We conducted a systematic review ... -
A combined strategies intervention on the World Health Organization prescribing indicators: A quasi-randomised trial.
( AOSIS Publishing , 2024 , Article)Irrational medicine use is a global problem that may potentiate antimicrobial resistance. This study aims to assess prescribing practices and the effect of a prescription audit and feedback coupled with small-group education ... -
Comparison of postoperative pain in children after maintenance anaesthesia with propofol or sevoflurane: a systematic review and meta-analysis.
( Elsevier , 2024 , Article Review)Propofol and sevoflurane are two of the most commonly used anaesthetics for paediatric surgery. Data from some clinical trials suggest that postoperative pain incidence is lower when propofol is used for maintenance of ... -
CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs
( Frontiers Media SA , 2024 , Article)Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM ... -
Metabolomic profiling reveals key metabolites associated with hypertension progression
( Frontiers Media SA , 2024 , Article)Introduction: Pre-hypertension is a prevalent condition among the adult population worldwide. It is characterized by asymptomatic elevations in blood pressure beyond normal levels but not yet reaching the threshold for ... -
Incidence, clinical features, and outcomes of posterior circulation ischemic stroke: insights from a large multiethnic stroke database
( Frontiers Media SA , 2024 , Article)Background: Posterior cerebral circulation ischemic stroke (PCS) comprises up to 25% of all strokes. It is characterized by variable presentation, leading to misdiagnosis and morbidity and mortality. We aim to describe PCS ... -
What Matters Most: Determinants Associated with the Selection of Medical Residencies in Qatar
( Dove Medical Press Ltd , 2024 , Article)Purpose: There have been several studies into medical student career decision making in occidental countries (eg US, UK), but medical career selection in a Middle Eastern context has not been as well studied. This study ... -
Estimates of the prevalence of male circumcision in sub-Saharan Africa from 2010-2023 -A systematic review and meta-analysis
( Public Library of Science , 2024 , Article)Background Male circumcision (MC) is a key part of the package of interventions to prevent HIV, the biggest health challenge in sub-Saharan Africa. Objective To estimate the male circumcision prevalence and to evaluate the ... -
Accuracy of procalcitonin for diagnosing sepsis in adult patients admitted to the emergency department: a systematic review and meta-analysis
( BioMed Central Ltd , 2024 , Article Review)Background Differentiating sepsis from non-infectious systemic inflammatory response syndrome (SIRS) is challenging. Biomarkers like procalcitonin (PCT) aid early risk assessment and guide antibiotic use. This study aims ... -
Breast lump as the initial presentation of metastatic uterine leiomyosarcoma: a case report and comprehensive literature review
( Medicinska Naklada Zagreb , 2024 , Article)Uterine leiomyosarcoma (uLMS) is a rare but aggressive cancer with a high metastatic potential and an unfavo-rable prognosis. A 54-year-old woman with a history of uterine fibroids clinically presented with a painless, ... -
Elucidating the chemical profile and biological studies of Verbascum diversifolium Hochst. extracts
( Frontiers Media SA , 2024 , Article)The present study was designed to evaluate the chemical composition, antioxidant, enzyme inhibition and cytotoxic properties of different extracts from aerial parts of V. diversifolium (family Scrophulariaceae), a plant ... -
A Path towards Timely VAP Diagnosis: Proof-of-Concept Study on Pyocyanin Sensing with Cu-Mg Doped Graphene Oxide
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)In response to the urgent requirement for rapid, precise, and cost-effective detection in intensive care units (ICUs) for ventilated patients, as well as the need to overcome the limitations of traditional detection methods, ... -
Status of Polymer Fused Deposition Modeling (FDM)-Based Three-Dimensional Printing (3DP) in the Pharmaceutical Industry
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Additive manufacturing (AM) or 3D printing (3DP) is arguably a versatile and more efficient way for the production of solid dosage forms such as tablets. Of the various 3DP technologies currently available, fused deposition ... -
The Contemporary Role of Hematopoietic Stem Cell Transplantation in the Management of Chronic Myeloid Leukemia: Is It the Same in All Settings?
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) patients has transitioned from the standard of care to a treatment option limited to those with unsatisfactory tyrosine kinase inhibitor ... -
Corrigendum: Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats (Frontiers in Pharmacology, (2023), 14, (1305816), 10.3389/fphar.2023.1305816)
( Frontiers Media SA , 2024 , Other)In the published article, there was an error in Figure 4A as published. During the last stage of revision, labels in Figure 4A were inadvertently altered, and the group labels in the figure were mistakenly substituted. The ... -
The Frequency, Severity, and Risk Factors of Hickman Catheter-Related Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina
( AVES , 2024 , Article)Objective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary ... -
Trilayer composite scaffold for urethral reconstruction: in vitro evaluation of mechanical, biological, and angiogenic properties
( IOP Publishing , 2024 , Article)Regeneration of damaged urethral tissue remains a major challenge in the field of lower urinary tract reconstruction. To address this issue, various synthetic and natural biodegradable biomaterials are currently being ...