College of Medicine: Recent submissions
Now showing items 221-240 of 1457
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
( Elsevier , 2023 , Article)In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type 2 diabetes ... -
Validation of plasma protein glycation and oxidation biomarkers for the diagnosis of autism
( Springer Nature , 2023 , Article)Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder in children. It is currently diagnosed by behaviour-based assessments made by observation and interview. In 2018 we reported a discovery study of a ... -
Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Purpose The liver-expressed antimicrobial peptide 2 (LEAP2) is a newly recognized peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) blunting the effects of ghrelin and displaying ghrelin-independent ... -
Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature
( Oxford University Press , 2023 , Article)Acute appendicitis is the most frequent cause of abdominal pain and acute emergency surgeries, with a mortality risk of 6-7% at its onset. Since atypical deviations in these structures are rare, they can lead to diagnosis ... -
Excision and reconstruction of dorsal nasal mucous cyst using dorsal nasal flap technique: a case report and literature review
( Oxford University Press , 2023 , Article)Congenital nasal masses are very rare presentations. Among these masses is a mucous cyst, which might be considered either a congenital or an acquired mass. Our report presents a case of recurrent dorsal nasal swelling ... -
A new simple and innovative technique for surgical drains fixation
( Oxford University Press , 2023 , Article)Seroma is a common complication post many plastic surgery procedures. To overcome this issue, drain insertion became a standard of care in many procedures. Existing methods for fixing the drain like the Roman sandal, purse ... -
Use of conditional estimates of effect in cancer epidemiology: An application to lung cancer treatment
( Elsevier , 2024 , Article)Background: In oncology clinical trials, there is the assumption that randomization sufficiently balances confounding covariates and therefore average treatment effects are usually reported. This paper explores the wider ... -
Demographic characteristics, laboratory features and complications in 346 cases of brucellosis: A retrospective study from Qatar
( Elsevier , 2024 , Article)Objectives: To study the epidemiology and laboratory findings and outcomes of human brucellosis in the state of Qatar. Methods: A retrospective study involving adult patients with a definitive diagnosis of brucellosis was ... -
Impact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018
( Taylor and Francis Ltd. , 2024 , Article)This study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio ... -
Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study
( Springer , 2024 , Article)Introduction: Alzheimer’s Disease (AD) is complex and novel approaches are urgently needed to aid in diagnosis. Blood is frequently used as a source for biomarkers; however, its complexity prevents proper detection. The ... -
Correction to: Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells (Cancers, (2021), 13, 22, (5741), 10.3390/cancers13225741)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Other)In the original publication [1], errors were identified in the published Figures 4 and 7. The original raw data of western blots could not be retrieved and therefore the experiments were redone to generate the corrected ... -
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
( Elsevier , 2023 , Article)Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ... -
Association between Diabetes and Levels of Micronutrients in Qatar—A Case–Control Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Objective: The objectives of this study were to investigate associations between micronutrient levels and diabetes and to explore the association in individuals with controlled and uncontrolled diabetes. Methods: A ... -
Effects of neratinib on angiogenesis and the early stage of the embryo using chicken embryo as a model.
( the Association of Basic Medical Sciences , 2023 , Article)Angiogenesis is the process of forming new blood capillaries from pre-existing vessels. Even though it is essential during normal development, it plays a major role in cancer progression. Neratinib is a pan-human epidermal ... -
Gastroduodenal Tuberculosis Presenting as a Gastric Outlet Obstruction: A Case Report.
( Springer , 2023 , Other)Abdominal tuberculosis (TB) can affect any part of the gastrointestinal tract, solid organs, peritoneum, or lymph nodes. The diagnosis of abdominal TB is usually delayed due to a lack of specific clinical signs and symptoms ... -
Scientometrics and academia.
( the Association of Basic Medical Sciences , 2023 , Other)The social significance and quality of every human activity are proportional to its usefulness to the social community. Science belongs to the very top of the processes and events in the history of humankind that strongly ... -
Response to Commentary “The correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of endoscopic reflux correction”
( Elsevier , 2023 , Other)Thank you very much for your interest and valuable comments regarding our study entitled “The correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of ... -
COVID-19 and Alzheimer's disease: Impact of lockdown and other restrictive measures during the COVID-19 pandemic.
( the Association of Basic Medical Sciences , 2023 , Article Review)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection initially results in respiratory distress symptoms but can also lead to central nervous system (CNS) and neurological manifestations, significantly ... -
No Association Between Ct Value and COVID-19 Severity and Mortality in Qatar.
( Dove Press Ltd , 2023 , Article)The association between the cycle threshold (Ct) which reflects the SARS-CoV-2 viral load and the severity of COVID-19 is still not clear. We investigated the association between Ct values, symptoms and the risk of ICU ... -
Mental health during COVID-19 in Qatar
( BMJ Publishing Group , 2020 , Other)The COVID-19 pandemic has posed unprecedented health and social challenges. WHO has been working to promote the integration of mental health and psychosocial support into the COVID-19 response effort.1 It is vital that ...