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AuthorSharifi, Shahriar
AuthorMahmoud, Nouf N
AuthorVoke, Elizabeth
AuthorLandry, Markita P
AuthorMahmoudi, Morteza
Available date2023-07-06T11:25:26Z
Publication Date2022-08-20
Publication NameNano-micro letters
Identifier10.1007/s40820-022-00922-5
Identifierhttp://dx.doi.org/10.1007/s40820-022-00922-5
CitationSharifi, S., Mahmoud, N. N., Voke, E., Landry, M. P., & Mahmoudi, M. (2022). Importance of standardizing analytical characterization methodology for improved reliability of the nanomedicine literature. Nano-micro letters, 14(1), 172.‏
URIhttp://hdl.handle.net/10576/45129
AbstractUnderstanding the interaction between biological structures and nanoscale technologies, dubbed the nano-bio interface, is required for successful development of safe and efficient nanomedicine products. The lack of a universal reporting system and decentralized methodologies for nanomaterial characterization have resulted in a low degree of reliability and reproducibility in the nanomedicine literature. As such, there is a strong need to establish a characterization system to support the reproducibility of nanoscience data particularly for studies seeking clinical translation. Here, we discuss the existing key standards for addressing robust characterization of nanomaterials based on their intended use in medical devices or as pharmaceuticals. We also discuss the challenges surrounding implementation of such standard protocols and their implication for translation of nanotechnology into clinical practice. We, however, emphasize that practical implementation of standard protocols in experimental laboratories requires long-term planning through integration of stakeholders including institutions and funding agencies.
Languageen
Publisherspringer link
SubjectCharacterization
Nanomedicine
Nanomedicine devices
Reproducibility
Standard protocols
TitleImportance of Standardizing Analytical Characterization Methodology for Improved Reliability of the Nanomedicine Literature.
TypeArticle
dc.accessType Open Access


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