Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 768
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Finite Element Analysis of Evolut Transcatheter Heart Valves: Effects of Aortic Geometries and Valve Sizes on Post-TAVI Wall Stresses and Deformations
( MDPI , 2025 , Article)Background/Objectives: For transcatheter aortic valve implantation (TAVI) therapy, a catheter-guided crimped valve is deployed into the aortic root. Valve types such as Edwards balloon-expandable valves and Medtronic ... -
Highly fluorescent push-pull bis-coumarinyl sulfone: Synthesis, photophysical behavior, and solvatochromic response
( Elsevier , 2025 , Article)In this work, 3,3′-sulfonylbis(7-(diethylamino)-2H-chromen-2-one), an effective fluorescent push-pull system, is synthesized and photophysically characterized. The donor-π–acceptor–π–donor (D–π–A–π–D) architecture of the ... -
Regioselective domino C–C/C–O arylation of 1,2,3-triiodobenzenes and 1,3-diketones: Synthesis and in silico evaluation of 7-iodobenzo[b]furan as potential ALK inhibitors
( Elsevier , 2025 , Article)We report a simple, direct, and regioselective protocol for the synthesis of 2,3-disubstituted 7-iodobenzo[b]furans via domino double CC/CO arylations of 1,2,3-triiodobenzene and 1,3-dicarbonyl compounds. Remarkably, the ... -
Machine learning for predicting outcomes of transcatheter aortic valve implantation: A systematic review
( Elsevier , 2025 , Article)BackgroundTranscatheter aortic valve implantation (TAVI) therapy has demonstrated its clear benefits such as low invasiveness, to treat aortic stenosis. Despite associated benefits, still post-procedural complications might ... -
Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD
( Springer Nature , 2025 , Article)Abstract: Aortic aneurysms pose a significant risk of rupture. Previous research has shown that areas exposed to low wall shear stress (WSS) are more prone to rupture. Therefore, precise WSS determination on the aneurysm ... -
Evaluating chemiluminescent immunoassays for syphilis detection: A comparative analysis
( Elsevier , 2025 , Article)BackgroundSyphilis, caused by Treponema pallidum (TP), remains a significant global public health concern, with approximately 8 million new cases annually. Diagnosing syphilis is challenging due to its often-asymptomatic ... -
Evaluating Hospital Admission Data as Indicators of COVID-19 Severity: A National Assessment in Qatar.
( Oxford University Press , 2025 , Article)Accurately assessing SARS-CoV-2 infection severity is essential for understanding the health impact of the infection and evaluating the effectiveness of interventions. This study investigated whether SARS-CoV-2-associated ... -
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
( Springer Nature , 2025 , Article)Background: Cancer cells can modulate the expression of many proteins that are essential for supporting their uncontrolled proliferation. Heat shock protein 90 (HSP90) is ubiquitously expressed in most cell types and ... -
The molecular mechanism of nitric oxide in memory consolidation and its role in the pathogenesis of memory-related disorders
( Springer Nature , 2025 , Article)Memory is a dynamic process of encoding, storing, and retrieving information. It includes sensory, short-term, and long-term memory, each with unique characteristics. Nitric oxide (NO) is a biological messenger synthesized ... -
Indications and clinical outcomes of percutaneous cholecystostomies in acute cholecystitis: a study from Qatar.
( BioMed Central , 2025 , Article)Acute cholecystitis (AC) is a prevalent condition in emergency departments (EDs). Standard care involves early laparoscopic cholecystectomy; however, in cases of delayed presentation, high surgical risk, or during situations ... -
Advancing Medical Research Through Artificial Intelligence: Progressive and Transformative Strategies: A Literature Review
( John Wiley & Sons , 2025 , Article)Background and Aims: Artificial intelligence (AI) has become integral to medical research, impacting various aspects such as data analysis, writing assistance, and publishing. This paper explores the multifaceted influence ... -
Seroprevalence of influenza A H1N1 and influenza D viruses in ruminants in Qatar
( Elsevier , 2025 , Article)BackgroundInfluenza is among the most common viruses affecting humans and many animals worldwide. While influenza A (IAV) and D (IDV) viruses are associated with respiratory disease in humans and animals, respectively, ... -
Association between clinical laboratory indicators and WOMAC scores in Qatar Biobank participants: The impact of testosterone and fibrinogen on pain, stiffness, and functional limitation
( Walter de Gruyter GmbH , 2025 , Article)Objectives: The association between baseline laboratory parameters and experienced well-being in healthy individuals remains uncertain. This study explored the relationship between clinical laboratory profiles and Western ... -
Unveiling GATA3 Signaling Pathways in Health and Disease: Mechanisms, Implications, and Therapeutic Potential
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)GATA binding protein 3 (GATA3), a member of the GATA family transcription factors, is a key player in various physiological and pathological conditions. It is known for its ability to bind to the DNA sequence "GATA", which ... -
Metformin-loaded nanoparticles reduce hyperglycemia-associated oxidative stress and induce eNOS phosphorylation in vascular endothelial cells
( Nature Research , 2024 , Article)Diabetes mellitus is a chronic disease characterized by metabolic defects, including insulin deficiency and resistance. Individuals with diabetes are at increased risk of developing cardiovascular complications, such as ... -
Metabarcoding analysis of oral microbiome during pregnancy
( Frontiers Media SA , 2024 , Article)Pregnancy is a dynamic physiological process involving significant hormonal, immune, and metabolic changes to support fetal growth and development. This study investigates the changes in salivary microbiome and biochemical ... -
Prevalence of SPOP and IDH Gene Mutations in Prostate Cancer in a Jordanian Population
( Springer , 2024 , Article)Speckle-type POZ (SPOP) is described as an essential tumor suppressor factor in gastric cancer, colorectal cancer, and prostate cancer (PCa). SPOP gene mutations were reported in primary human PCa. Isocitrate dehydrogenase-1 ... -
GATA3: Orchestrating cellular fate through differentiation and proliferation
( Elsevier , 2025 , Article Review)Cell proliferation and differentiation are two fundamental biological processes that occur in biological systems, tightly regulated by various factors such as transcription factors (TFs). Zinc finger proteins are TFs ... -
Mindray CL-900i assay: An effective assay for hepatitis B surface antigen screening with superior specificity
( Elsevier , 2025 , Article)Objectives The chemiluminescence immunoassay automated Abbott ARCHITECT hepatitis B surface antigen (HBsAg) screening assay is globally recognized for its superior sensitivity but notably low specificity. This mandates ... -
Molecular identification and characterization of waterborne protozoa among stranded Dugong dugon
( Elsevier , 2025 , Article)The Persian Gulf hosts the second-largest population of Dugongs. The International Union for the Conservation of Nature (IUCN) lists them as Vulnerable to Extinction species. Incidental fishing, vessel strikes, environmental ...
