Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 421 -- 440 من 711
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Level of Maternal Respiratory Syncytial Virus (RSV) F Antibodies in Hospitalized Children and Correlates of Protection.
(2021)RSV is a major cause of lower respiratory infections among children, where no vaccine is available. The stabilized form of the fusion (F) protein, pre-F, is a leading vaccine candidate targeting different populations, ... -
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
( Nature Research , 2021 , Article)Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ... -
Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
( MDPI , 2021 , Article)Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of ... -
EndMT regulation by small RNAs in diabetes-associated fibrotic conditions: potential link with oxidative stress
( Frontiers Media , 2021 , Article)Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ dysfunction, disability, and increased mortality. ... -
Genetic Diversity and Prevalence of in Qatar.
( Frontiers Media , 2021 , Article)is a common human intestinal parasite worldwide, and the causative agent of diarrhea, with the severity of disease ranging from asymptomatic to intense and debilitating infection. is known to consist of eight genetically ... -
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery - A Follow-Up Study
( Dovepress , 2021 , Article)Obesity is a chronic disorder characterized by a low-grade inflammatory state and immune cell irregularities. The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory ... -
A Cross-Sectional Study on Bullying and Psychological Disturbances among Malaysian School Children
( Universitas Indonesia , 2021 , Article)Abstract Background: Bullying is a common violence in school and has become a major public health and global concern. Bullying influences mental health and is identified as a leading factor of depression. Therefore, this ... -
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
( Taylor and Francis Ltd , 2016 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
The Promise of the Zebrafish Model for Parkinson’s Disease: Today’s Science and Tomorrow’s Treatment
( Frontiers Media , 2021 , Article)The second most prevalent neurodegenerative disorder in the elderly is Parkinson’s disease (PD). Its etiology is unclear and there are no available disease-modifying medicines. Therefore, more evidence is required concerning ... -
Thymoquinone, as a Novel Therapeutic Candidate of Cancers
( MDPI , 2021 , Article)To date, natural products are widely used as pharmaceutical agents for many human diseases and cancers. One of the most popular natural products that have been studied for anticancer properties is thymoquinone (TQ). As ... -
The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap
( Frontiers Media , 2021 , Article Review)Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ... -
Activation of the pro-oxidant PKC?IIp66Shc Signaling pathway contributes to pericyte dysfunction in skeletal muscles of patients with diabetes with critical limb Ischemia
( American Diabetes Association Inc. , 2016 , Article)Critical limb ischemia (CLI), foot ulcers, former amputation, and impaired regeneration are independent risk factors for limb amputation in subjects with diabetes. The present work investigates whether and by which mechanism ... -
Sulforaphane Downregulates Hepatic Fibroblast Growth Factor 21 (FGF21) of Diet Induced Obese Mice
( The Obesity Society , 2020 , Conference Paper)Background: Fibroblast growth factor 21 is a hormone-like protein that plays a critical role as an energy regulator. Sulforaphane (SFN) is expected to have potential therapeutic effects in treating obesity. This study aims ... -
Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris
( Frontiers Media , 2021 , Article)Background: Oxidative stress has been implicated as a fundamental mechanism in the decline of bone mass. Although serum uric acid (SUA) has potent antioxidant properties, the findings of many epidemiological and experimental ... -
Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis.
( BMC , 2021 , Report)Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial dysbiosis ... -
Thymoquinone Suppresses Cell Proliferation and Enhances Apoptosis of HL60 Leukemia Cells through Re-Expression of JAK/STAT Negative Regulators.
( West Asia Organization for Cancer Prevention (WAOCP) , 2021 , Article)The natural compound, thymoquinone (TQ) has demonstrated potential anticancer properties in inhibiting cell proliferation and promoting apoptosis in myeloid leukemia cells, breast cancer cells, and others. However, the ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ... -
Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries: A Systematic Review.
( Lippincott, Williams & Wilkins , 2021 , Article)Alzheimer disease (AD) is a progressive and complex neurodegenerative disease. Approximately 70% of AD risk is attributed to genetic risk factors, including variants in amyloid precursor protein (APP), presenilin 1 (PSEN1), ... -
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
( Elsevier , 2021 , Article)Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ... -
SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections
( Elsevier , 2021 , Article)By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...