Biomedical Sciences: Recent submissions
Now showing items 501-520 of 711
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Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
( MDPI , 2020 , Article Review)Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ... -
The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: a systematic review
( Elsevier , 2020 , Article)Backgroundthe recent outbreak of the coronavirus disease 2019 (COVID‐19) has quickly spread globally since its discovery in Wuhan, China, in December 2019. A comprehensive strategy, including surveillance, diagnostics, ... -
Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
( Elsevier , 2020 , Article)Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ... -
Drosophila as a Model Organism in Host–Pathogen Interaction Studies
( Frontiers Media , 2020 , Article Review)Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ... -
Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin.
( MDPI , 2020 , Article)The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle, offering the optional property of delivering drugs as a single dose rather than in multiple doses. The current study aims to improve ... -
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
( Elsevier , 2020 , Article)Breast cancer (BC) is one of the leading causes of cancer-related death among women worldwide, and claudin-low breast cancer (CLBC) is a subtype of BC that remains poorly described. This study aimed to identify upregulated ... -
Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma.
( MDPI , 2020 , Article)Asthma is a chronic inflammatory condition linked to hyperresponsiveness in the airways. There is currently no cure available for asthma, and therapy choices are limited. Asthma is the result of the interplay between genes ... -
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
( MDPI , 2020 , Article)E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ... -
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach.
( Frontiers Media , 2020 , Article)Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder that is clinically complex and has increased production of autoantibodies. Via emerging technologies, researchers have identified genetic variants, ... -
Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2
( MDPI , 2020 , Article)The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, ... -
Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio)
( MDPI , 2020 , Article)Despite their wide industrial use, Zinc oxide (ZnO) nanoparticles (NPs) exhibit a high toxic potential while concerns of their health-related risks are still present, urging additional in vivo clarification studies. ... -
Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region
( MDPI , 2020 , Article)Respiratory syncytial virus (RSV) is one of the most common viruses to infect children worldwide and is the leading cause of lower respiratory tract illness (LRI) in infants. This study aimed to conduct a systematic review ... -
Antihypertensive indigenous lebanese plants: Ethnopharmacology and a clinical trial
( MDPI AG , 2019 , Article)Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study ... -
Prevalence of general and abdominal obesity among adolescents attending independent schools in Qatar
( Emerald Group Publishing Ltd. , 2019 , Article)Purpose: The purpose of this paper is to determine the prevalence of general and abdominal obesity among adolescents attending independent schools in Qatar. Design/methodology/approaches: A school-based cross-sectional ... -
Investigation of the genetic structure of Kabyle and Chaouia Algerian populations through the polymorphism of Alu insertion markers
( Taylor and Francis Ltd , 2019 , Article)Background: In Algeria, as in all North Africa, Berbers constitute the old background of the population. Today, Berber speakers account for only ∼ 25% of Algerians. This decline is the product of a complex human settlement ... -
Special appreciations are given to top five peer-reviewers of journal of food quality and hazards control in 2018
( Shahid Sadoughi University of Medical Sciences , 2019 , Article)[No abstract available] -
MicroRNAs in Cardiac Hypertrophy
( MDPI AG , 2019 , Article Review)Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress and pathological conditions. Cardiac remodeling could be ... -
Molecular epidemiology of Rotavirus in children with gastroenteritis in Qatar
( OMICS , 2019 , Conference Paper)Acute gastroenteritis remains a major cause of morbidity and mortality of young children worldwide. The vast majority of diarrhea cases in developing and developed countries are attributable to the viruses and to a lesser ... -
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: a novel therapeutic target in early endothelial dysfunction of metabolic disease
( Elsevier Ltd , 2019 , Article Review)Over the past three decades, our view of the endothelium rapidly evolved from a static lining of the blood vessels to a dynamic determinant and regulator of vascular tone and homeostasis. It is now widely accepted that ... -
Therapeutic angiogenesis: From conventional approaches to recent nanotechnology-based interventions
( Elsevier Ltd , 2019 , Article Review)Intentional and regulated induction of blood vessels formation which is generally referred to as therapeutic angiogenesis has a lot of potential in the management of various kinds of ischemic complications as well as in ...