Health Sciences-CAS (pre 2016): Recent submissions
Now showing items 61-80 of 151
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Study protocol: Mother and Infant Nutritional Assessment (MINA) cohort study in Qatar and Lebanon
( BioMed Central , 2016 , Article)Background The Middle East and North Africa region harbors significant proportions of stunting and wasting coupled with surging rates of non-communicable diseases (NCDs). Recent evidence identified nutrition during the ... -
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
( Taylor & Francis , 2015 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
( Multidisciplinary Digital Publishing Institute (MDPI) , 2016 , Article)The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ... -
PHYSICAL INACTIVITY AS A PREDICTOR OF HYPERTENSION AMONG EMPLOYEES IN SRI LANKA: A CROSS-SECTIONAL STUDY
( Wolters Kluwer Health, Inc. , 2016 , Conference)Background: There is compelling evidence that physical inactivity is responsible for a large proportion of non-communicable diseases. It is estimated that approximately 2 million deaths every year are attributable to ... -
WORKSITE HEALTH PROMOTION SCORE: TO ASSESS A HEALTH PROMOTIONAL WORKER SETTING
( Wolters Kluwer Health , 2016 , Conference)Objective: Workplace play a central role in the lives of employees and their potential as health-promotional-setting is enormous as it could aim at keeping employees healthy which is considered a key long-term human asset ... -
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
( Hindawi Publishing Corporation , 2015 , Article)Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ... -
The Dual Role of Paramagnetic Particles for Integrated Lysis and Measurement in a Rapid Immunoassay for Intracellular Proteins
( IEEE , 2013 , Article)Abstract—A novel, integrated lysis and immunoassay method- ology and system for intracellular protein measurement are de- scribed. The method uses paramagnetic particles both as a lysis agent and assay label resulting ... -
Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases
(2016 , Poster)Background: Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ... -
The prevalence of vitamin D deficiency among female college students at Qatar University
( Medical Services Department Saudi Arabian Armed , 2011 , Article)Nowadays vitamin D deficiency is considered as a common problem among many Arab countries including Lebanon, Qatar, Saudi Arabia, UAE and other European countries as documented by many studies (1,2,3,5). Vitamin D is a ... -
Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles
( Elsevier B.V. , 2013 , Article)Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and ... -
Detection and Genotyping of Torque Teno Virus (TTV) in Healthy Blood Donors and Patients Infected With HBV or HCV in Qatar
( Wiley Periodicals, Inc , 2015 , Article)Torque Teno virus (TTV) has been associated with non A–G hepatitis. The goal of this study was to estimate the infection rates and genotypic characteristics of TTV in the State of Qatar. A total of 644 blood samples ... -
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
( Public Library of Science (USA) , 2016 , Article)Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell ... -
First Study in Qatar to Reveal High Legionella Count in Cooling Towers
( Oxford University Press - ASCP , 2015 , Article)Legionella is an intracellular bacterium that can cause a severe communityacquired and nosocomial pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments, including manmade water ... -
A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10
( Akadémiai Kiadó , 2015 , Article)L. pneumophila is an intracellular bacterium that replicates inside a membrane- bound vacuole called Legionella-containing vacuole (LCV), where it plentifully liberates its HtpB chaperonin. From LCV, HtpB reaches the ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Deletion of potD, encoding a putative spermidine-binding protein, results in a complex phenotype in Legionella pneumophila
( Elsevier GmbH , 2014 , Article)L. pneumophila is an intracellular pathogen that replicates in a membrane-bound compartment known as the Legionella-containing vacuole (LCV). We previously observed that the polyamine spermidine, produced by host cells or ... -
Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing
( Future Medicine , 2016 , Article)Wound dressings play an important role in a patient’s recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ... -
Metagenomic analysis demonstrates the diversity of the fecal virome in asymptomatic pigs in East Africa
( Springer Vienna , 2016 , Article)Pigs harbor a variety of viruses that are closely related to human viruses and are suspected to have zoonotic potential. Little is known about the presence of viruses in smallholder farms where pigs are in close contact ... -
Is it the time for Hepatitis E virus (HEV) Testing for Blood Donors in Qatar?
( Qatar Foundation , 2016 , Conference)HEV is the etiologic agent of acute hepatitis E. Although HEV usually causes a self-limiting infection, the disease may develop into a chronic or fulminant form of Hepatitis. Sporadic HEV infections spread in several ... -
Time Dependent Assessment of Morphological Changes: Leukodepleted Packed Red Blood Cells Stored in SAGM
( Hindawi , 2016 , Article)Usually packed red blood cells (pRBCs) require specific conditions in storage procedures to ensure the maximum shelf life of up to 42 days in 2–6°C. However, molecular and biochemical consequences can affect the stored ...
