Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study.
Author | Mohammedain, Shahd A |
Author | Badran, Saif |
Author | Elzouki, AbdelNaser Y |
Author | Salim, Halla |
Author | Chalaby, Ayesha |
Author | Siddiqui, Mya |
Author | Hussein, Yehia Y |
Author | Rahim, Hanan Abdul |
Author | Thalib, Lukman |
Author | Alam, Mohammed Fasihul |
Author | Al-Badriyeh, Daoud |
Author | Al-Maadeed, Sumaya |
Author | Doi, Suhail Ar |
Available date | 2023-11-28T05:00:09Z |
Publication Date | 2023-10-01 |
Publication Name | Future Virology |
Identifier | http://dx.doi.org/10.2217/fvl-2023-0036 |
Citation | Mohammedain SA, Badran S, Elzouki AY, Salim H, Chalaby A, Siddiqui M, Hussein YY, Rahim HA, Thalib L, Alam MF, Al-Badriyeh D, Al-Maadeed S, Doi SA. Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study. Future Virol. 2023 Oct:10.2217/fvl-2023-0036. doi: 10.2217/fvl-2023-0036. Epub 2023 Nov 7. PMID: 37970094; PMCID: PMC10630949. |
ISSN | 1746-0794 |
Abstract | This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients were recruited at their initial diagnosis at two facilities within Hamad Medical Corporation in Qatar. 356 adults were included for analysis. Predictors for progression of COVID-19 were all measured at disease onset and first contact with the health system. The C statistic was 83% (95% CI: 78%-87%) and the calibration plot showed that the model was well-calibrated. The published prognostic model for the progression of COVID-19 infection showed satisfactory discrimination and calibration and the model is easy to apply in clinical practice.d. |
Sponsor | This study was approved by the medical ethics committee of Qatar University and Hamad Medical Corporation (protocol nuos. QU-IEB 1434-E/20 and MRC 05-137, respectively) and written informed consent was obtained from all participants. |
Language | en |
Publisher | Future Medicine |
Subject | COVID-19 disease severity prognosis risk prediction |
Type | Article |
ESSN | 1746-0808 |
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