Medicine Research
Recent Submissions
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Ṯābit Ibn Qurrah’s contributions to toxicology
( Springer , 2024 , Article Review)Mankind has been familiar with poisons since ancient times. On the other hand, there is a wealth of knowledge in the medical books including medieval works of Middle Eastern polymaths such as Avicenna, “al-Rāzī,” and “Ṯābit ... -
Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study
( John Wiley and Sons Ltd , 2024 , Article)Objectives: To estimate lifetime prevalence, risk, and treatment for mental disorders and their correlates in Qatar's general population for the first time. Methods: We conducted a national phone survey of 5,195 Qatari and ... -
Evaluating the accuracy of population-specific versus generic stature estimation regression equations in a South African sample
( Springer , 2024 , Article)Accurate estimates of stature play an important role in the personal identification of unknown decedents, however a drawback in the application of many stature estimation equations is the need for known sex and population, ... -
Development of a 43 color panel for the characterization of conventional and unconventional T-cell subsets, B cells, NK cells, monocytes, dendritic cells, and innate lymphoid cells using spectral flow cytometry
( John Wiley and Sons Inc , 2024 , Article)Although many flow cytometers can analyze 30–50 parameters, it is still challenging to develop a 40+ color panel for the phenotyping of immune cells using fluorochrome conjugated antibodies due to limitations in the ... -
Cumulative Incidence of Venous Thromboembolic Events In-Hospital, and at 1, 3, 6, and 12 Months After Metabolic and Bariatric Surgery: Systematic Review of 87 Studies and Meta-analysis of 2,731,797 Patients
( Springer , 2024 , Article Review)Abstract: Systematic review/meta-analysis of cumulative incidences of venous thromboembolic events (VTE) after metabolic and bariatric surgery (MBS). Electronic databases were searched for original studies. Proportional ... -
How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly
( Springer , 2024 , Article)Background: The aim of this study was to delineate the features of the locomotive syndrome (LS) risk stage in the elderly population, encompassing global spine sagittal alignment, visible spinal degenerative changes on ... -
Recalcitrant pityriasis rubra pilaris in a Middle Eastern patient and arguments for early anti-IL-23 targeting
( John Wiley and Sons Inc , 2024 , Article)Pityriasis rubra pilaris (PRP) is a rare, chronic cutaneous inflammatory disorder of keratinization affecting adults, children and patients with HIV. The pathogenesis of PRP is not fully understood with clinical presentations, ... -
Twelve-month prevalence, persistence, severity, and treatment of mood and anxiety disorders in Qatar's national mental health study
( John Wiley and Sons Ltd , 2024 , Article)Objectives To estimate 12-month prevalence, persistence, severity, and treatment of mental disorders and socio-demographic correlates in Qatar. Methods We conducted the first national population-based telephone survey ... -
Formulations and mechanisms of action of novel vaccine adjuvants
( Elsevier , 2024 , Book chapter)Vaccine adjuvants play a critical role in inducing optimal adaptive immune responses. Vaccine adjuvants can be lipids, metal-based, pathogen-based, and plant-based compounds. Few vaccine adjuvants are licensed for use in ... -
Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis
( Springer , 2024 , Article)Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3 (NCT03732807) study, the oral JAK3/TEC family kinase inhibitor ... -
Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases
( Elsevier , 2024 , Article Review)IL-36 is a most recent member of the IL-1 cytokine family, primarily expressed at barrier sites of the body such as the skin, lungs, and intestine. It plays a vital role in inflammation and is implicated in the development ... -
Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with post-repair complications
( Elsevier , 2024 , Article)Objectives The Plate Objective Scoring Tool (POST) accurately reflects configuration of the urethral plate in distal hypospadias. Here we assessed whether POST score also correlates with patient risk of complications after ... -
Urologist validation of an artificial intelligence-based tool for automated estimation of penile curvature
( Elsevier , 2024 , Article)Introduction Severity of penile curvature (PC) is commonly used to select the optimal surgical intervention for hypospadias, either alone or in conjunction with other phenotypic characteristics. Despite this, current ... -
Flushing New Light on Rosacea
( Elsevier , 2024 , Article)The study "Integrated omics reveal the molecular characterization and pathogenic mechanism of rosacea" (Zhang et al, 2023) presents the first multiomics integrative analysis comparing proteomic and transcriptomic signatures ... -
The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
( Elsevier , 2024 , Article Review)Head and neck cancer (HNC) is the sixth most common cancer type, accounting for approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) agents ... -
Chronic inflammation and cancer; the two sides of a coin
( Elsevier , 2024 , Article Review)The correlation between chronic inflammation and cancer was initially identified in the 19th century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors, and adhesion molecules, which regulate ... -
Hypospadias-associated penile curvature assessment and management: A global survey of current practice
( Elsevier , 2024 , Article)Introduction: Our goal was to assess how surgical management of hypospadias-associated penile curvature (HAPC) varies across continents, focusing on factors that influence assessment and decision-making. Methods: Members ... -
Effects of dietary curcumin on gene expression: An analysis of transcriptomic data in mice
( Elsevier , 2024 , Article Review)BACKGROUND: Curcumin, a ubiquitous polyphenol in turmeric, possesses many anti-cancer and anti-inflammatory properties. These therapeutic effects are largely resultant of curcumin's ability to modulate global gene expression. ... -
The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis
( Elsevier , 2024 , Article Review)This systematic review and meta-analysis aimed to provide guidance on preoperative blood transfusion strategies for patients with sickle cell disease (SCD). We included all randomized controlled and observational studies ... -
Flavonoids, gut microbiota and cardiovascular disease: Dynamics and interplay
( Elsevier , 2024 , Article Review)Cardiovascular disease (CVD) remains the leading cause of global morbidity and mortality. Extensive efforts have been invested to explicate mechanisms implicated in the onset and progression of CVD. Besides the usual ...
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