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AuthorSulaiman, Aliyu
AuthorIsah, Mohammad Alfa
AuthorUsman, Abubakar
Available date2024-04-29T08:29:14Z
Publication Date2024-02-09
Publication NameExpert Review of Anti-Infective Therapy
Identifierhttp://dx.doi.org/10.1080/14787210.2024.2307913
CitationSulaiman, A., Isah, M. A., & Usman, A. (2024). An assessment of the index of rational drug prescribing for severe acute respiratory infections among hospitalised children in Northern Nigeria: a retrospective study. Expert Review of Anti-infective Therapy, 1-8.
ISSN1478-7210
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85184871981&origin=inward
URIhttp://hdl.handle.net/10576/54441
AbstractBackground: This study evaluated drug use pattern among hospitalized children with severe acute respiratory infection (SARI) in Nigeria. Research design and methods: A retrospective assessment of prescribed medicines for children aged 13 years and below who were admitted and treated for SARI from 1 January 2016 to 31 December 2018 was conducted. The WHO prescribing indicators and the Index of Rational Drug Prescribing were used to evaluate prescriptions. Results: A total of 259 patients were included, mostly diagnosed with bronchopneumonia (56%). A summary of WHO-core prescribing indicators showed the average number of drugs per encounter was 3.9, medicines prescribed by generic name was 82.1%, and an encounter with at least an antibiotic was 99.7%. The percentage of drugs prescribed from the Essential Medicine List for children was 79%. The most frequently prescribed pharmacological class of medicines was antibiotics (41.4%). Cephalosporins (40.0%), aminoglycosides (34.1%), and penicillins (21.5%) were the most commonly prescribed antibiotic classes. Gentamicin (34.1%) and cefuroxime (21.5%) were the most commonly prescribed antibiotics. Conclusions: Drug prescribing for hospitalized children with SARI was suboptimal, especially with regard to polypharmacy, antibiotics, and injection use. Interventions to promote rational use of medicines including antimicrobial stewardship interventions are recommended.
SponsorOpen Access funding provided by the Qatar National Library.
Languageen
PublisherTaylor & Francis
Subjectantibiotic prescribing
children
severe acute respiratory infections
Use of medicines
WHO prescribing indicators
TitleAn assessment of the index of rational drug prescribing for severe acute respiratory infections among hospitalised children in Northern Nigeria: a retrospective study
TypeArticle
Pagination1-8
ESSN1744-8336
dc.accessType Open Access


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