Browsing Biomedical Research Center by Author "Wheatley, Adam K"
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Immunomodulation Induced by Host Pathogen Interaction
Yassine, Hadi M.; Moin, Syed M.; Cyprian, Farhan S.; Wheatley, Adam K.; Nasrallah, Gheyath K. ( Hindawi , 2019 , Article)Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune ... -
Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation
Villar, Rina F.; Patel, Jinal; Weaver, Grant C.; Kanekiyo, Masaru; Wheatley, Adam K.; Yassine, Hadi M.; Costello, Catherine E.; Chandler, Kevin B.; McTamney, Patrick M.; Nabel, Gary J.; McDermott, Adrian B.; Mascola, John R.; Carr, Steven A.; Lingwood, Daniel... more authors ... less authors ( Nature Publishing Group , 2016 , Article)Activation of immune cells (but not B cells) with lectins is widely known. We used the structurally defined interaction between influenza hemagglutinin (HA) and its cell surface receptor sialic acid (SA) to identify a B ...