Browsing Biomedical Research Center by Publication Date
Now showing items 21-40 of 709
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E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation
( Taylor & Francis , 2015 , Article)It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ... -
Reference ranges of lymphocyte subsets in healthy Qatari adults
( Future Medicine Ltd , 2015 , Article)Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. Patients & Methods: Blood samples (n = 150) were investigated using four colors flow cytometery. Results: The mean percentage and absolute ... -
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
( Dove Press , 2015 , Article)Iron–manganese-doped sulfated zirconia nanoparticles with both Lewis and Brønsted acidic sites were prepared by a hydrothermal impregnation method followed by calcination at 650°C for 5 hours, and their cytotoxicity ... -
The distribution of Blastocystis subtypes in isolates from Qatar
( BioMed Central Ltd. , 2015 , Article)Background: Blastocystis is a common single-celled intestinal parasite of humans and other animals comprising at least 17 genetically distinct small subunit ribosomal RNA lineages (subtypes (STs)), nine of which have been ... -
First Study in Qatar to Reveal High Legionella Count in Cooling Towers
( Oxford University Press - ASCP , 2015 , Article)Legionella is an intracellular bacterium that can cause a severe communityacquired and nosocomial pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments, including manmade water ... -
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
( Future Medicine , 2015 , Article)Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ... -
Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications
( Multidisciplinary Digital Publishing Institute (MDPI) , 2015 , Article)A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. ... -
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
( Wiley , 2015 , Article)Human Pegivirus (HPgV), formerly GB virus-C/ Hepatitis G virus (GBV-C/HGV), collectively known as GBV-C, is widely spread and has been reported to be associated with non-A–E hepatitis. To our knowledge, no previous ... -
The Qatar Biobank: background and methods
( BioMed Central , 2015 , Article)Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ... -
Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells
( Spandidos Publications , 2016 , Article)Patients with cancer often exhibit signs of anemia as the result of the disease. Thus, cancer chemotherapies often include erythropoietin (EPO) in the regime to improve the survival rate of these patients. The aim of the ... -
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
( Bentham Science , 2016 , Book chapter)Alzheimer's disease (AD) is a complex neurodegenerative condition that is clinically characterized by impaired cognitive functions. The major morphologically observed lesion of AD encompasses the accumulation of extracellular ... -
Chromosome aberrations and fertility disorders in domestic animals
( Annual Reviews Inc. , 2016 , Article Review)The association between chromosomal abnormalities and reduced fertility in domestic animals is well recorded and has been studied for decades. Chromosome aberrations directly affect meiosis, gametogenesis, and the viability ... -
DNA-based influenza vaccines as immunoprophylactic agents toward universality
( Future Medicine Ltd. , 2016 , Article Review)Influenza is an illness of global public health concern. Influenza viruses have been responsible for several pandemics affecting humans. Current influenza vaccines have proved satisfactory safety; however, they have ... -
Molecular and Peritoneal Microvascular Changes Cause Peritoneal Membrane Dysfunction by Uremia-Related Mechanisms
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Long-term peritoneal dialysis (PD) is associated with distinct peritoneal structural changes characterized by thickening of the sub-mesothelial cell layer, fibrosis and angiogenesis. These changes were assumed to be the ... -
Prevalence of Gastrointestinal Protoz in Feral Cat Population in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Introduction: Doha city has a high feral cat population that is estimated to outnumber its human inhabitants by 2-3:1 with a total population of 2-3 million cats according to Qatar Cat Control Unit (QCCU). Doha had a ... -
The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculation
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Traumatic exsanguination leading to class IV hemorrhagic shock as defined by the Committee on Trauma of the American College of Surgeons requires aggressive resuscitation with crystalloids and packed cells together with ... -
Helminth Infections Among Long-Term-Residents and Settled Immigrants in Qatar in the Decade from 2005 to 2014: Temporal Trends and Varying Prevalence Among Subjects from Different Regional Origins
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)We analysed the prevalence of helminth infection in a dataset of 31,008 records of subjects referred for stool examination at the Hamad Medical Corporation over the course of a decade (2005 to 2014, inclusive). Overall ... -
Effectiveness of antipseudomonal antibiotics and mechanisms of multidrug resistance in Pseudomonas aeruginosa
( Polish Society of Microbiologists , 2016 , Article)Pseudomonas aeruginosa is a leading human pathogen that causes serious infections at various tissues and organs leading to life threatening health problems and possible deadly outcomes. Resistance patterns vary widely ... -
The eutherian pseudoautosomal region
( S. Karger AG , 2016 , Article Review)The pseudoautosomal region (PAR) is a unique segment of sequence homology between differentiated sex chromosomes where recombination occurs during meiosis. Molecular and functional properties of the PAR are distinctive ... -
A Non-Reciprocal Autosomal Translocation 64,XX, t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss
( Blackwell Publishing Ltd , 2016 , Article)Contents: Balanced autosomal translocations are a known cause for repeated early embryonic loss (REEL) in horses. In most cases, carriers of such translocations are phenotypically normal, but the chromosomal aberration ...