Browsing by Subject "Doxorubicin"
Now showing items 1-6 of 6
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Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells
( Spandidos Publications , 2016 , Article)Patients with cancer often exhibit signs of anemia as the result of the disease. Thus, cancer chemotherapies often include erythropoietin (EPO) in the regime to improve the survival rate of these patients. The aim of the ... -
The Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced Cardiotoxicity
( OMICS International , 2015 , Article)Background: Doxorubicin (DOX), a widely used anticancer drug, has been associated with cardiotoxicity. Recently, DOX-induced cardiotoxicity has been attributed to topoisomerase II (TOPII)-β expression and activity. In our ... -
Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity
( Springer Nature , 2024 , Article)Background: Doxorubicin (DOX) is a potent chemotherapy widely used in treating various neoplastic diseases. However, the clinical use of DOX is limited due to its potential toxic effect on the cardiovascular system. Thus, ... -
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
( S. Karger AG , 2016 , Conference Paper)This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ... -
Polymethyl methacrylate–ovalbumin @ graphene oxide drug carrier system for high anti-proliferative cancer drug delivery
( Springer Nature , 2019 , Article)High permeable drug delivery mechanism is indispensable for the treatment of various diseases including cancer. Protein-polymeric carriers have enhanced the permeability and therapeutic of bioactive compounds. Here, ... -
Vulnerabilities of the SARS-CoV-2 virus to proteotoxicity - opportunity for repurposed chemotherapy of COVID-19 infection
( Qatar University Press , 2020 , Poster)The global pandemic of COVID-19 disease caused by infection with the SARS-CoV-2 coronavirus, has produce an urgent requirement and search for improved treatments whilst effective vaccines are developed. A strategy for ...