Synthesis of some new oximes, thiocarbamates, pyrazolyloxy, isoxazolyloxy, Pyrmidyloxy and pyridyloxy quinolines

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Author Abdel Hafez, Ali A. [علي عبد الحافظ] en_US
Available date 2009-11-25T15:28:30Z en_US
Publication Date 1994 en_US
Citation Qatar University Science Journal, 1994, Vol. 14, No. خاص, Pages 108-113. en_US
URI http://hdl.handle.net/10576/10155 en_US
Abstract The reaction of 1 or its corresponding chalcones 3a-c with hydroxylamine in boiling pyridine gave the oximes 2 or 5a-c respectively in almost quantitative yield. When both 2 and 5a-c were reacted with phenylisothiocyanate, the corresponding thiocarbamates 4 and 6a-c were achieved. A new series of pyrazolyloxy 7a-f, isoxazolyloxy 8a-c, pyrimidyloxy 9a-f and pyridyloxy 10a,b quinolines were obtained from the reaction of 3a-c with hydrazines, hydroxylamine, urea, thiourea and malononitrile respectively. The in vitro antibacterial and antifungal activity were screened for all the compounds prepared, some of the compounds tested showed interesting results. en_US
Abstract يتفاعل مركب 5 - مورفو. ar
Language en en_US
Publisher Qatar University en_US
Subject Organic Chemistry en_US
Subject الكيمياء العضوية ar
Title Synthesis of some new oximes, thiocarbamates, pyrazolyloxy, isoxazolyloxy, Pyrmidyloxy and pyridyloxy quinolines en_US
Alternative Title مركبات جديدة لمشتقات 8 - كينولين - أوكسي أسيتيل أوكزيم - ثيوكربامات - أزولات - بريميدينات والنيكوتينونيتريل ar
Type Article en_US


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