Browsing Medicine Research by Title
Now showing items 665-684 of 1418
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Identification of a Histone Deacetylase: Epigenetic Impact on Host Gene Expression.
( MDPI , 2020 , Article)Epigenetic reprogramming in macrophages is termed trained innate immunity, which regulates immune tolerance and limits tissue damage during infection. is a strict human pathogen that causes the sexually transmitted infection ... -
Identification of a 48 kDa form of unconventional myosin 1c in blood serum of patients with autoimmune diseases.
( Elsevier , 2016 , Article)We searched for protein markers present in blood serum of multiple sclerosis (MS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients in comparison to healthy human individuals. We used precipitati ... -
Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
( Oxford University Press , 2020 , Article)The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ... -
Identification of Co-Deregulated Genes in Urinary Bladder Cancer Using High-Throughput Methodologies
( MDPI , 2021 , Article)Urinary bladder cancer (UBC) is the second most common urogenital solid tumor and the eleventh in the rank among all types of solid tumors. Although several oncogenes and tumor suppressors are known to be implicated in the ... -
Identification of cortactin molecular forms in human urine and their possible diagnostic value
( Palladin Institute of Biochemistry of the NASU , 2021 , Article)The protein composition of human urine reflects changes in the biochemical and physiological status of an individual and has an essential diagnostic value. Using precipitation/extraction methods we isolated a protein with ... -
Identification of FAM173B as a protein methyltransferase promoting chronic pain
( Public Library of Science , 2018 , Article)Chronic pain is a debilitating problem, and insights in the neurobiology of chronic pain are needed for the development of novel pain therapies. A genome-wide association study implicated the 5p15.2 region in chronic ... -
Identification of potential transcription factors that enhance human iPSC generation
( Springer Nature , 2020 , Article)Although many factors have been identified and used to enhance the iPSC reprogramming process, its efficiency remains quite low. In addition, reprogramming efficacy has been evidenced to be affected by disease mutations ... -
Identification of SER-PRO-CYS Peptide in Blood Serum of Multiple Sclerosis Patients
( Bentham Science Publishers , 2016 , Article)Monitoring of multiple sclerosis (MS) requires additional molecular markers. Recently, we used original TCA-precipitation/extraction approach in combination with MALDI TOF/TOF mass-spectrometry and identified earlier unknown ... -
Identifying essential competencies for medical students
( Emerald Group Publishing Ltd. , 2019 , Article)Purpose The purpose of this paper is to identify essential profession-related competencies, clinical knowledge and skills that medical students should develop in the early stages of their education for future professional ... -
Identifying metabolic alterations in newly diagnosed small cell lung cancer patients
( Elsevier , 2021 , Article)BackgroundSmall cell lung cancer (SCLC) is a malignant disease with poor prognosis. At the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is based on imaging, histopathology, and ... -
IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group’s Criteria
( Elsevier , 2021 , Article)AimsThe approaches used to screen and diagnose gestational diabetes mellitus (GDM) vary widely. We generated a comparable estimate of the global and regional prevalence of GDM by International Association of Diabetes in ... -
IDF Diabetes Atlas: The prevalence of pre-existing diabetes in pregnancy – A systematic reviewand meta-analysis of studies published during 2010–2020
( Elsevier , 2021 , Article)ObjectivesTo estimate the prevalence of pre-existing diabetes in pregnancy from studies published during 2010–2020. MethodsWe searched PubMed, CINAHL, Scopus and other sources for relevant data sources. The prevalence of ... -
ILK silencing inhibits migration and invasion of more invasive glioblastoma cells by downregulating ROCK1 and Fascin-1.
( Springer , 2020 , Article)Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor and it is associated with poor survival. Integrin-linked kinase (ILK) is a serine/threonine protein pseudo-kinase that binds to the cytoplasmic domains ... -
Immunisation against COVID-19 in Pregnancy and of Women Planning Pregnancy
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Following reports of the first human SARS-CoV2 infection in December 2019 from Wuhan Province, China, there was such rapid spread that by March 2021, the World Health Organization (WHO) had declared a pandemic. Over 6.5 ... -
Immunofluorescence Staining of Paraffin Sections Step by Step.
( Frontiers Media , 2020 , Article)Immunofluorescence staining is the most frequently applied technique to detect and visualize various molecules in biological samples. Many protocols can be found in the literature and the websites of commercial antibody ... -
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
( Elsevier , 2021 , Article)There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ... -
Immunohistochemistry-Enabled Precision Medicine
( Springer, Cham , 2019 , Book chapter)Immunohistochemistry (IHC) can be applied to diagnostic aspects of pathologic examination to provide aid in assignment of lineage and histologic type of cancer. Increasingly, however, IHC is widely used to provide prognostic ... -
Immunomodulation Induced by Host Pathogen Interaction
( Hindawi , 2019 , Article)Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune ... -
Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond.
( Frontiers Media , 2019 , Article)In addition to its role in calcium homeostasis and bone formation, a modulatory role of the active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been described. The effects of vitamin D ... -
Immunotherapy and immunoevasion of colorectal cancer
( Elsevier , 2023 , Article Review)The tremendous success of immunotherapy in clinical trials has led to its establishment as a new pillar of cancer therapy. However, little clinical efficacy has been achieved in microsatellite stable colorectal cancer ...