A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
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Abstract The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based FRET system, this assay achieved a sensitivity and specificity of 98.6% and 90% respectively.
http://hdl.handle.net/10576/5605 ; http://dx.doi.org/10.1016/j.mimet.2017.06.001
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