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Author Al Fahhad, Marwan. A. [مروان الفهد]en_US
Available date 2009-11-25T15:18:45Zen_US
Publication Date 2003en_US
Publication Name Qatar University Science Journal
Citation Qatar University Science Journal, 2003, Vol. 23, Pages 77-86.en_US
URI http://hdl.handle.net/10576/9862en_US
Abstract Synthetic red blood cells known as LEH is a material that offers an excellent alternative to substitution blood since the chemical composition of the Oxy, LEH, is similar to that of the natural blood cells. Unfortunately, this alternative, like the natural blood, has a limited shelf life at room temperature due to thermal and/or solar (optical) radiations exposure. In this study experiments were run on LEH assays, with and without protection additives, to weigh up the effect of exposing LEH to thermal effect, using a digital controlled oven, and to optical radiations, using an appropriate apparatus to simulate the solar optical radiations. Constant evaluation of the acceptability of this artificial blood alternative was done with the help of an advanced computerized technique. The results of the experiment have shown that exposing LEH to thermal and optical radiations leads to a reduction of the concentration of the oxyhemoglobin and a heightened of the concentration of the methemoglobin. The rate of LEH degra dation in the two treatments was linked to the time in which they were exposed both to the thermal and optical radiations effects. Antioxidants, ascorbic acid and alfa-tocopherol were used in order to conserve and guard the prepared LEH from the degradation that happens to it due to the effects of both thermal and optical radiations.en_US
Language enen_US
Publisher Qatar Universityen_US
Subject Biological Scienceen_US
Subject بيولوجياar
Title Thermal and Optical Radiation Effects on LEHen_US
Alternative Title التأثير الحرارى والضوئي على كريات الدم الحمراء المصنعةar
Type Articleen_US
Pagination 77-86en_US
Volume Number 23en_US
Alternative Abstract تصلح كريات الدم الحمراء المصنعة المعروفة باسم ل.ا.هـ كبديل ممتاز في عمليات نقل الدم ، وهى منافس جيد لنقل الأوكسجين ، تماما كما تفعل كريات الدم الحمراء الطبيعية،. ولكن للأسف فان هذا البديل الصناعي يشبه الدم الطبيعي في قصر مدة الحياة عندما يحفظ على الرف في درجة حرارة الغرفة العادية، وذلك نظرا لتأثره بالإشعاع الحرارى والضوئي . في هذه الدراسة تم عمل تحاليل حول عمل كريات الدم الحمراء المصنعة، مع وبدون اضافات للحماية .


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