Browsing by Author "Zissimopoulos, Spyros"

Now showing items 1-2 of 2

    • Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. 

      Seidel, Monika; de Meritens, Camille Rabesahala; Johnson, Louisa; Parthimos, Dimitris; Bannister, Mark; ... more authors ( Oxford University Press , 2020 , Article)
      The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ...

    • Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation 

      Yin, Liheng; Jr, Alexandra Zahradnikova; Rizzetto, Riccardo; Boncompagni, Simona; Meritens, Camille Rabesahala de; ... more authors ( American Heart Association , 2021 , Article)
      RATIONALE: Catecholaminergic polymorphic ventricular tachycardia is a rare disease, manifested by syncope or sudden death in children or young adults under stress conditions. Mutations in the Ca2+ release channel/type 2 ...