Browsing by Author "Abu-Raddad, Laith J."
Now showing items 1-20 of 87
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All-cause and COVID-19 mortality in Qatar during the COVID-19 pandemic
Alnuaimi, Asma A.; Chemaitelly, Hiam; Semaan, Sandy; Almukdad, Sawsan; Al-Kanaani, Zaina; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Al-Romaihi, Hamad Eid; Butt, Adeel A.; Al-Thani, Mohamed H.; Bertollini, Roberto; Abdulmalik, Mariam; Al-Khal, Abdullatif; Abu-Raddad, Laith J.... more authors ... less authors ( BMJ Publishing Group , 2023 , Article)Objective To investigate all-cause mortality, COVID-19 mortality and all-cause non-COVID-19 mortality in Qatar during the COVID-19 pandemic. Methods A national, retrospective cohort analysis and national, matched, retrospective ... -
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Chemaitelly, Hiam; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Rahim, Hanan F Abdul; Yassine, Hadi M; Al Kuwari, Mohamed G; Qotba, Hamda; Al Romaihi, Hamad Eid; Tang, Patrick; Bertollini, Roberto; Al-Thani, Mohamed H; Althani, Asmaa A; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2021 , Article)Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ... -
Analyzing inherent biases in SARS-CoV-2 PCR and serological epidemiologic metrics
Makhoul, Monia; Abou-Hijleh, Farah; Seedat, Shaheen; Mumtaz, Ghina R.; Chemaitelly, Hiam; Ayoub, Houssein; Abu-Raddad, Laith J.... more authors ... less authors ( springer nature , 2022 , Article)Background: Prospective observational data show that infected persons with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain polymerase chain reaction (PCR) positive for a prolonged duration, and that ... -
Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination
Zedan, Hadeel T.; Smatti, Maria K.; Thomas, Swapna; Nasrallah, Gheyath K.; Afifi, Nahla M.; Hssain, Ali Ait; Abu Raddad, Laith J.; Coyle, Peter V.; Grivel, Jean Charles; Almaslamani, Muna A.; Althani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( American Medical Association , 2023 , Article)Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ... -
Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study
Shurrab, Farah M.; Al-Sadeq, Duaa W.; Abou-Saleh, Haissam; Al-Dewik, Nader; Elsharafi, Amira E.; Hamaydeh, Fatima M.; Abo Halawa, Bushra Y.; Jamaleddin, Tala M.; Abdul Hameed, Huda M.; Nizamuddin, Parveen B.; Amanullah, Fathima Humaira; Daas, Hanin I.; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2022 , Report)The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2. Recently, it was ... -
Assessment of the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection in an Intense Reexposure Setting
Abu-Raddad, Laith J.; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; Younuskunju, Shameem; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Butt, Adeel A.; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F.; Yassine, Hadi M.; Al Kuwari, Mohamed G.; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Bertollini, Roberto... more authors ... less authors ( NLM (Medline) , 2021 , Article)BACKGROUND: Risk of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We assessed the risk and incidence rate of documented SARS-CoV-2 reinfection in a cohort of laboratory-confirmed ... -
Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar.
Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; Tang, Patrick; Hasan, Mohammad R; Coyle, Peter; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Butt, Adeel A; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto... more authors ... less authors ( American Medical Association , 2021 , Article)The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ... -
Associations of Vaccination and of Prior Infection with Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar
Bertollini, Roberto; Chemaitelly, Hiam; Yassine, Hadi M.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Abu-Raddad, Laith J.... more authors ... less authors ( American Medical Association , 2021 , Other)The SARS-CoV-2 pandemic has severely affected international travel. With efficacious COVID-19 vaccines available, Qatar implemented a pilot program between February 18 and April 26, 2021, to ease travel restrictions by ... -
Bivalent mRNA-1273.214 vaccine effectiveness against SARS-CoV-2 omicron XBB* infections
Chemaitelly, Hiam; Ayoub, Houssein H.; AlMukdad, Sawsan; Faust, Jeremy S.; Tang, Patrick; Coyle, Peter; Yassine, Hadi M.; Al Thani, Asmaa A.; Al-Khatib, Hebah A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors (2023 , Article)In October of 2022, Qatar introduced COVID-19 bivalent vaccination for persons ≥ 12 years using the 50-μg mRNA-1273.214 vaccine combining SARS-CoV-2 ancestral and omicron BA.1 strains.1 We estimated this vaccine’s effectiveness ... -
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
Tang, Patrick; Hasan, Mohammad R; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; AlMukdad, Sawsan; Coyle, Peter; Ayoub, Houssein H; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Butt, Adeel A; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Nature Researc , 2021 , Article)With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Al-Khatib, Hebah A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Al-Romaihi, Hamad Eid; Butt, Adeel A.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
Ismail, Ahmed; Shurrab, Farah M; Al-Jighefee, Hadeel T; Al-Sadeq, Duaa W; Qotba, Hamda; Al-Shaar, Ibrahim Abdu; Yassine, Hadi M; Abu-Raddad, Laith J; Nasrallah, Gheyath K... more authors ... less authors ( IMR , 2021 , Article)Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ... -
Characterizing epidemiology of prediabetes, diabetes, and hypertension in Qataris: A cross-sectional study
Al-Thani, Mohammed H.; Al-Mutawa, Kholood A.; Alyafei, Salah A.; Ijaz, Muhammad A.; Khalifa, Shamseldin A.H.; Kokku, Suresh B.; Mishra, Amit C.M.; Poovelil, Benjamin V.; Soussi, Mounir B.; Toumi, Amine A.; Dargham, Soha R.; Awad, Susanne F.; Abu-Raddad, Laith J.... more authors ... less authors ( Public Library of Science , 2021 , Article)Objectives To characterize the epidemiologic profiles of prediabetes mellitus (preDM), diabetes mellitus (DM), and hypertension (HTN) in Qataris using the nationally representative 2012 Qatar STEPwise Survey. Methods A ... -
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; Al Kanaani, Zaina; Al Kuwari, Einas; Butt, Adeel A; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Nasrallah, Gheyath K; Benslimane, Fatiha M; Al Khatib, Hebah A; Yassine, Hadi M; Al Kuwari, Mohamed G; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Kha, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J; Ayoub, Houssein H... more authors ... less authors ( International Society of Global Health , 2022 , Article)Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ... -
Characterizing the Qatar advanced-phase SARS-CoV-2 epidemic
Abu-Raddad, Laith J.; Chemaitelly, Hiam; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Butt, Adeel A.; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Owen, Robert C.; Rahim, Hanan F.Abdul; Al Abdulla, Samya A.; Al Kuwari, Mohamed G.; Kandy, Mujeeb C.; Saeb, Hatoun; Ahmed, Shazia Nadeem N.; Al Romaihi, Hamad Eid; Bansal, Devendra; Dalton, Louise; Al-Thani, Mohamed H.; Bertollini, Roberto... more authors ... less authors ( springer nature , 2021 , Article)The overarching objective of this study was to provide the descriptive epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Qatar by addressing specific research questions through a ... -
Characterizing trends and associations for hepatitis C virus antibody prevalence in the Middle East and North Africa: meta-regression analyses
Mahmud, Sarwat; Chemaitelly, Hiam; Alaama, Ahmed S.; Hermez, Joumana G.; Abu-Raddad, Laith J. ( Springer Nature , 2022 , Article)This study characterized population-level trends and associations with hepatitis C virus (HCV) antibody (Ab) prevalence in the Middle East and North Africa (MENA). Data source was the standardized and systematically gathered ... -
Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; Ahmed, Muna N.; El-kahlout, Reham A.; Al Bader, Mashael A.; Elgakhlab, Dina; Coyle, Peter V.; Abu-Raddad, Laith J.; Al Thani, Asma A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ... -
Coronavirus Disease 2019 Disease Severity in Children Infected With the Omicron Variant
Butt, A.A.; Butt, Adeel A.; Dargham, Soha R.; Loka, Srusvin; Shaik, Riyazuddin M.; Chemaitelly, Hiam; Tang, Patrick; Hasan, Mohammad R.; Coyle, Peter V.; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Kaleeckal, Anvar H.; Latif, Ali Nizar; Zaqout, Ahmed; Almaslamani, Muna A.; Al Khal, Abdullatif; Bertollini, Roberto; Abou-Samra, Abdul Badi; Abu-Raddad, Laith J.... more authors ... less authors ( NLM (Medline) , 2022 , Article)SHORT SUMMARY: Severe acute respiratory syndrome coronavirus 2 infection from the Omicron variant in children/adolescents is less severe than infection from the Delta variant. Those 6 to <18 years also have less severe ... -
COVID-19 Disease Severity in Persons Infected with Omicron BA.1 and BA.2 Sublineages and Association with Vaccination Status
Butt, Adeel A.; Dargham, Soha R.; Coyle, Peter; Yassine, Hadi M.; Al-Khal, Abdullatif; Abou-Samra, Abdul Badi; Abu-Raddad, Laith J.... more authors ... less authors ( American Medical Association , 2022 , Other)[No abstract available] -
Covid-19 Vaccine Protection among Children and Adolescents in Qatar.
Chemaitelly, Hiam; AlMukdad, Sawsan; Ayoub, Houssein H; Altarawneh, Heba N; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H; Latif, Ali N; Shaik, Riyazuddin M; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed G; Al-Romaihi, Hamad E; Butt, Adeel A; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses. We assessed the real-world ...