Browsing by Author "n 97923942"
Now showing items 61-80 of 100
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M cell targeting engineered biomaterials for effective vaccination
ArifulIslam, Mohammad; Firdous, Jannatul; Badruddoza, Abu Zayed Md; Reesor, Emma; Azad , Mohammad; Hasan, Anwarul; Lim, Michael; Cao, Wuji; Guillemette, Simon; SuCho, Chong... more authors ... less authors ( Elsevier Ltd , 2019 , Article)Vaccines are one of the greatest medical interventions of all time and have been successful in controlling and eliminating a myriad of diseases over the past two centuries. Among several vaccination strategies, mucosal ... -
Magnetic nanocatalysts as multifunctional platforms in cancer therapy through the synthesis of anticancer drugs and facilitated Fenton reaction
Khan S.; Sharifi M.; Hasan, Anwarul; Attar F.; Edis Z.; Bai Q.; Derakhshankhah H.; Falahati M.... more authors ... less authors ( Elsevier B.V. , 2021 , Article)Background: Heterocyclic compounds have always been used as a core portion in the development of anticancer drugs. However, there is a pressing need for developing inexpensive and simple alternatives to high-cost and complex ... -
Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury.
Hasan, Anwarul; Deeb, George; Rahal, Rahaf; Atwi, Khairallah; Mondello, Stefania; Marei, Hany Elsayed; Gali, Amr; Sleiman, Eliana; Hasan, Anwarul... more authors ... less authors ( Frontiers Media , 2017 , Article)Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The ... -
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
Saoud R.; Jaffa M.A.; Habib A.; Zhao J.; Al Hariri M.; Zhu R.; Hasan, Anwarul; Ziyadeh F.N.; Kobeissy F.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ... -
MXene Nanosheets May Induce Toxic Effect on the Early Stage of Embryogenesis.
Alhussain, Hashim; Augustine, Robin; Hussein, Essraa A; Gupta, Ishita; Hasan, Anwarul; Al Moustafa, Ala-Eddin; Elzatahry, Ahmed... more authors ... less authors ( American Scientific Publishers , 2020 , Article)MXene (Ti₃C₂T), as a novel 2D material, has produced a great interest due to its promising properties in biomedical applications, nevertheless, there is a lack of studies dedicated to investigate the possible toxic effect ... -
Nanoengineered biomimetic hydrogels for guiding human stem cell osteogenesis in three dimensional microenvironments
Paul, Arghya; Manoharan, Vijayan; Krafft, Dorothee; Assmann, Alexander; Uquillas, Jorge Alfredo; Shin, Su Ryon; Hasan, Anwarul; Hussain, Mohammad Asif; Memic, Adnan; Gaharwar, Akhilesh K.; Khademhosseini, Ali... more authors ... less authors ( Royal Society of Chemistry , 2016 , Article)The ability to modulate stem cell differentiation in a three dimensional (3D) microenvironment for bone tissue engineering in the absence of exogenous pharmaceutical agents such as bone morphogenic protein (BMP-2) remains ... -
Nanoporous iron oxide nanoparticle: hydrothermal fabrication, human serum albumin interaction and potential antibacterial effects
Mehrabi M.; Ghasemi M.F.; Rasti B.; Falahati M.; Mirzaie A.; Hasan, Anwarul... more authors ... less authors ( Taylor and Francis Ltd. , 2021 , Article)Nanoporous iron oxide (Fe3O4) nanoparticles (NIONPs) have been widely used as promising agents in biomedical applications. Herein, the NIONPs were synthesized by one-step hydrothermal method and well-characterized by FESEM ... -
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
Hasan, Anwarul; Nanakali N.M.Q.; Salihi A.; Rasti B.; Sharifi M.; Attar F.; Derakhshankhah H.; Mustafa I.A.; Abdulqadir S.Z.; Falahati M.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ... -
Natural halloysite nanotubes /chitosan based bio-nanocomposite for delivering norfloxacin, an anti-microbial agent in sustained release manner
Barman M.; Mahmood S.; Augustine R.; Hasan, Anwarul; Thomas S.; Ghosal K.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Applying nanotechnology to deliver drug could result in several benefits such as prolong duration of action, enhancement in overall bioavailability, targeting to specific site, low initial loading dose require, systemic ... -
Ni-P-ZrC nanocomposite coating with enhanced corrosion resistance and mechanical properties.
Fayyaz, Osama; Shakoor, R. A.; Hasan, Anwarul; Montemor, M. F.; Gao, Wei; Rasul, Shahid; Khan, Kashif; Iqbal Faruque, Mohammad Rashed... more authors ... less authors ( Qatar University Press , 2021 , Poster)Corrosion is considered to be greatest challenge for many industries. Nickel-based metallic coatings are emerging as one of the most suitable solution considering various aspects of operating conditions. The current ... -
NiFe2O4/poly(ethylene glycol)/lipid-polymer hybrid nanoparticles for anti-cancer drug delivery
Joshy K.S.; Augustine R.; Mayeen A.; Alex S.M.; Hasan, Anwarul; Thomas S.; Chi H.... more authors ... less authors ( Royal Society of Chemistry , 2020 , Article)The present study reports the fabrication of hybrid nanoparticles consisting of nickel ferrite (NFO) for anti cancer drug delivery. The hybrid system was formulated from poly(vinyl alcohol)/stearic acid with PEG containing ... -
Novel drug delivery systems based on triaxial electrospinning based nanofibers
Ghosal K.; Augustine R.; Zaszczynska A.; Barman M.; Jain A.; Hasan, Anwarul; Kalarikkal N.; Sajkiewicz P.; Thomas S.... more authors ... less authors ( Elsevier B.V. , 2021 , Article)Electrospinning is a widely investigated process for forming nanofibers. Nanofibers in drug delivery systems are extensively tested due to its remarkable properties e.g. small pore size or large surface area. Recent articles ... -
Novel electrodeposited Ni-B/Y 2 O 3 composite coatings with improved properties
Shakoor, Rana Abdul; Waware, Umesh Somaji; Ali, Kamran; Kahraman, Ramazan; Popelka, Anton; Yusuf, Moinuddin Mohammed; Hasan, Anwarul... more authors ... less authors ( MDPI AG , 2017 , Article)Ni-B/Y 2 O 3 composite coatings were developed through an electrodeposition process to study the effect of addition of Y 2 O 3 particles on structure, surface, thermal, mechanical, and anticorrosion properties of Ni-B ... -
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
Augustine, Robin; Alhussain, Hashim; Hasan, Anwarul; Badie Ahmed, Mohamed; C Yalcin, Huseyin; Al Moustafa, Ala-Eddin... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article)Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ... -
Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis
Abdelaziz Mohamed I.; Gadeau A.-P.; Hasan, Anwarul; Abdulrahman N.; Mraiche F. ( NLM (Medline) , 2019 , Article)Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recognized as a cytokine with pro-inflammatory actions. More recently, OPN has emerged as a ... -
Oxygen generating polymeric nano fibers that stimulate angiogenesis and show efficient wound healing in a diabetic wound model
Zehra M.; Zubairi W.; Hasan, Anwarul; Butt H.; Ramzan A.; Azam M.; Mehmood A.; Falahati M.; Anwar Chaudhry A.; Ur Rehman I.; Yar M.... more authors ... less authors ( Dove Medical Press Ltd. , 2020 , Article)Introduction: Diabetic wounds are challenging to treat due to a wide range of pathophysiological changes. Hypoxia is one of the predominant contributing factors of poor vascularization and chronicity in diabetic wounds. ... -
p53 signaling in cancer progression and therapy
Marei H.E.; Althani A.; Afifi N.; Hasan, Anwarul; Caceci T.; Pozzoli G.; Morrione A.; Giordano A.; Cenciarelli C.... more authors ... less authors ( BioMed Central Ltd , 2021 , Article)The p53 protein is a transcription factor known as the "guardian of the genome" because of its critical function in preserving genomic integrity. The TP53 gene is mutated in approximately half of all human malignancies, ... -
Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Callistemon citrinus Phenolics Exhibited Anticancer Properties against Three Breast Cancer Cell Lines
Ahmed, Rashid; Tariq, Muhammad; Ahmad, Irfan S.; Fouly, Hanafy; Fakhar-I-Abbas; Hasan, Anwarul; Kushad, Mosbah... more authors ... less authors ( Hindawi Limited , 2019 , Article)Fruit and vegetable diets rich in phenolic compounds reduce the risk of various cancers and offer multiple other health benefits due to their bioactivity and powerful antioxidant properties. However, the human health ... -
Polymeric-based microneedle arrays as potential platforms in the development of drugs delivery systems
Meng F.; Hasan, Anwarul; Mahdi Nejadi Babadaei M.; Hashemi Kani P.; Jouya Talaei A.; Sharifi M.; Cai T.; Falahati M.; Cai Y.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Background: Microscopic patches as quite promising platforms in transdermal drug delivery suffer from conventional injections. In other hand, a wide range of pharmacokinetics, ranging from fast oral administration to ... -
Potential of antibody-drug conjugates (ADCs) for cancer therapy
Marei, Hany E.; Cenciarelli, Carlo; Hasan, Anwarul ( BioMed Central Ltd , 2022 , Article Review)The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution and targeting specific cells. Antibody conjugates (ADCs) have changed the way cancer is treated. ...