Browsing by Author "Al-Khatib, Hebah A"

Now showing items 21-40 of 46

    • Influenza, RSV, and Other Respiratory Infections among Children in Qatar 

      Smatti, Maria K.; Al-Romaihi, Hamad E.; Al-Khatib, Hebah A.; Coyle, Peter V.; Al Thani, Asmaa A.; ... more authors ( Qatar University Press , 2020 , Poster)
      Background: Acute respiratory infections (ARIs) lead to high rates of mortality and morbidity among children. However, studies on the etiology of respiratory infections among children in Qatar and surrounding countries are ...

    • Intake of Caffeine Containing Sugar Diet Remodels Gut Microbiota and Perturbs Drosophila melanogaster Immunity and Lifespan 

      Abeer, Qush; Al Khatib, Hebah A.; Rachid, Hajar; Al-Tamimi, Hend; Al-Eshaq, Alyaa; ... more authors ( Elsevier , 2023 , Article)
      The diet-microbiome-immunity axis is one among the many arms that draw up the “we are what we intake” proclamation. As such, studies on the effect of food and beverage intake on the gut environment and microbiome and on ...

    • Inter-Versus Intra-Host Sequence Diversity of pH1N1 and Associated Clinical Outcomes 

      Al Khatib, Hebah A.; Al Maslamani, , Muna A.; V. Coyle, Peter; Thompson, I. Richard Thompson; A. Farag, Elmoubasher; ... more authors ( MDPI , 2020 , Article)
      The diversity of RNA viruses dictates their evolution in a particular host, community or environment. Here, we reported within- and between-host pH1N1virus diversity at consensus and sub-consensus levels over a three-year ...

    • Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis. 

      Sohail, Muhammad U; Al Khatib, Hebah A; Al Thani, Asmaa A; Al Ansari, Khalid; Yassine, Hadi M; ... more authors ( BMC , 2021 , Report)
      Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial dysbiosis ...

    • Molecular and biological characterization of influenza A viruses isolated from human fecal samples 

      Al Khatib, Hebah A.; Coyle, Peter V.; Al Maslamani, Muna A.; Al Thani, Asmaa A.; Pathan, Sameer A.; ... more authors ( Elsevier , 2021 , Article)
      Human influenza viruses are occasionally detected in the stools of influenza patients. Objectives: Here, we investigated the molecular and biological characteristics of intestinal influenza viruses and their potential role ...

    • Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012–2017) 

      Al-Romaihi, Hamad E.; Smatti, Maria K.; Al-Khatib, Hebah A.; Coyle, Peter V.; Ganesan, Nandakumar; ... more authors ( Elsevier B.V. , 2020 , Article)
      Background: Studies on the etiology of respiratory infections among children in Qatar and surrounding countries are limited. Objectives: To describe the prevalence and seasonality of RSV, influenza, and other respiratory ...

    • mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar 

      Chemaitelly, Hiam; Yassine, Hadi M.; Benslimane, Fatiha M.; Al Khatib, Hebah A.; Tang, Patrick; ... more authors (2021 , Article)
      The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ...

    • Nanomedicine as a Potential Tool against Monkeypox. 

      Mohamed, Nura Adam; Zupin, Luisa; Mazi, Sarah Ismail; Al-Khatib, Hebah A; Crovella, Sergio ( MDPI , 2023 , Article Review)
      Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ...

    • Nanopore Sequencing SARS-CoV-2 genome in Qatar 

      Benslimane, Fatiha M.; Al Khatib, Hebah; Albatesh, Dana; Al-Jamal, Ola; Boughattas, Sonia; ... more authors ( Qatar University Press , 2020 , Poster)
      Background: The current pandemic, COVID-19, is cause by an RNA coronavirus that was recently identified as SARS-CoV-2. RNA viruses tend to have a high mutation rate; the rate is around a million times greater than that of ...

    • One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar 

      Benslimane, Fatiha M; Al Khatib, Hebah A; Al-Jamal, Ola; Albatesh, Dana; Boughattas, Sonia; ... more authors ( Frontiers , 2021 , Article)
      Qatar, a country with a strong health system and a diverse population consisting mainly of expatriate residents, has experienced two large waves of COVID-19 outbreak. In this study, we report on 2634 SARS-CoV-2 whole-genome ...

    • Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; ... more authors ( Oxford University Press , 2021 , Article)
      Strategies for rolling out vaccination against Coronavirus Disease 2019 (Covid-19) varied across countries. A key question is whether delaying administration of the second vaccine dose to vaccinate the largest number of ...

    • Population immunity of natural infection, primary-series vaccination, and booster vaccination in Qatar during the COVID-19 pandemic: an observational study 

      Suelen H., Qassim; Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; ... more authors ( Elsevier , 2023 , Article)
      BackgroundWaning of natural infection protection and vaccine protection highlight the need to evaluate changes in population immunity over time. Population immunity of previous SARS-CoV-2 infection or of COVID-19 vaccination ...

    • Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses 

      Al Khatib, Hebah A.; Mathew, Shilu; Smatti, Maria K.; Eltai, Nahla O.; Pathan, Sameer A.; ... more authors ( MDPI , 2021 , Article)
      Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared the effect of influenza types, A and B, and influenza shedding in patients’ stools on ...

    • Protection against Reinfection with the Omicron BA.2.75 Subvariant 

      Chemaitelly, Hiam; Tang, Patrick; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; ... more authors ( Massachusetts Medical Society , 2023 , Other)
      The BA.2.75 sublineage of the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may escape neutralizing antibodies. The BA.2.75 sublineage (primarily the BA.2.75.2 subvariant) ...

    • Protection against the omicron variant from previous SARS-CoV-2 infection 

      Altarawneh, Heba N.; Chemaitelly, Hiam; Hasan, Mohammad R.; Ayoub, Houssein H.; Qassim, Suelen; ... more authors ( Massachusetts Medical Society , 2022 , Other)
      Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits strong protection against reinfection with the B.1.1.7 (alpha),1,2 B.1.351 (beta),1 and B.1.617.2 (delta)3 variants. However, the ...

    • Protection from previous natural infection compared with mRNA vaccination against SARS-CoV-2 infection and severe COVID-19 in Qatar: a retrospective cohort study 

      Hiam, Chemaitelly; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; ... more authors ( Elsevier , 2022 , Article)
      BackgroundUnderstanding protection conferred by natural SARS-CoV-2 infection versus COVID-19 vaccination is important for informing vaccine mandate decisions. We compared protection conferred by natural infection versus ...

    • Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Nature Research , 2022 , Article)
      There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...

    • Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity 

      Fakhroo, Aisha; AlKhatib, Hebah A; Al Thani, Asmaa A; Yassine, Hadi M ( MDPI , 2021 , Article)
      The COVID-19 pandemic is still posing a devastating threat to social life and economics. Despite the modest decrease in the number of cases during September-November 2020, the number of active cases is on the rise again. ...

    • Relative infectiousness of SARS-CoV-2 vaccine breakthrough infections, reinfections, and primary infections. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Tang, Patrick; Coyle, Peter; ... more authors ( Springer , 2022 , Article)
      SARS-CoV-2 breakthrough infections in vaccinated individuals and in those who had a prior infection have been observed globally, but the transmission potential of these infections is unknown. The RT-qPCR cycle threshold ...

    • Severity, Criticality, and Fatality of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Beta Variant 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; ... more authors ( Oxford Academic , 2021 , Article)
      Beta (B.1.351) variant COVID-19 disease was investigated in Qatar. Compared to Alpha (B.1.1.7) variant, odds of progressing to severe disease were 1.24-fold (95% CI: 1.11-1.39) higher for Beta. Odds of progressing to ...