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المؤلفAl Moustafa, Ala-Eddin
المؤلفAl-Antary, Noor
المؤلفAboulkassim, Tahar
المؤلفAkil, Nizar
المؤلفBatist, Gerald
المؤلفYasmeen, Amber
تاريخ الإتاحة2019-10-16T07:30:39Z
تاريخ النشر2016-07-02
اسم المنشورHuman Vaccines & Immunotherapeutics
المعرّفhttp://dx.doi.org/10.1080/21645515.2016.1139255
الاقتباسAla-Eddin Al Moustafa, Noor Al-Antary, Tahar Aboulkassim, Nizar Akil, Gerald Batist & Amber Yasmeen (2016) Co-prevalence of Epstein–Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer, Human Vaccines & Immunotherapeutics, 12:7, 1936-1939, DOI: 10.1080/21645515.2016.1139255
الرقم المعياري الدولي للكتاب2164-5515
معرّف المصادر الموحدhttp://hdl.handle.net/10576/12130
الملخصABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we report that EBV and high-risk HPVs are co-present in breast cancer in Syrian women. Therefore, and based on our previous studies and present data, we reveal that 35 (32%) of 108 cancer samples are positive for both EBV and high-risk HPVs and their co-presence is associated with high grade invasive ductal carcinomas (IDCs) with at least one positive lymph nodes, in comparison with EBV and high-risk HPVs-positive samples, which are low to intermediate grade IDCs, respectively. Future studies are needed to confirm the co-presence and the cooperation effect of these onco-viruses in human breast carcinogenesis and metastasis.
راعي المشروعThis work was supported by the Canadian Institutes for Health Research (CIHR) and the Fonds de la Recherche en Santé du Québec (FRSQ- Réseau du Cancer). The new research lab of Dr. Al Moustafa is supported by the College of Medicine at Qatar University.
اللغةen
الناشرTaylor & Francis
الموضوعEBV
Syrian women
breast cancer
cancer phenotype
high-risk HPV
العنوانCo-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
النوعArticle
الصفحات1936–1939
رقم العدد7
رقم المجلد12
ESSN2164-554X
dc.accessType Open Access


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