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AuthorMalki, Mohammed I
AuthorGupta, Ishita
AuthorFernandes, Queenie
AuthorAboulkassim, Tahar
AuthorYasmeen, Amber
AuthorVranic, Semir
AuthorAl Moustafa, Ala-Eddin
AuthorAl-Thawadi, Hamda A
Available date2020-03-22T09:48:21Z
Publication Date2020-03-18
Publication NameHuman Vaccines and Immunotherapeutics
Identifierhttp://dx.doi.org/10.1080/21645515.2020.1726680
CitationMohammed I. Malki, Ishita Gupta, Queenie Fernandes, Tahar Aboulkassim, Amber Yasmeen, Semir Vranic, Ala-Eddin Al Moustafa & Hamda A. Al-Thawadi (2020) Co-presence of Epstein–Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples, Human Vaccines & Immunotherapeutics, DOI: 10.1080/21645515.2020.1726680
ISSN2164-5515
URIhttp://hdl.handle.net/10576/13478
AbstractWe recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, we report that EBV and high-risk HPVs are co-present in colorectal cancers from Syria. We reveal that 17 (~17%) of 102 cancer samples are positive for both EBV and high-risk HPVs and their co-presence is associated with high/intermediate grade invasive carcinomas. These data suggest that EBV and high-risk HPVs are co-present in human colorectal cancers where they might cooperate on the initiation and/or progression of these cancers. Thus, we believe that future studies are necessary to confirm the co-presence of these oncoviruses and their cooperative role in human colorectal carcinogenesis.
SponsorThis work was supported by grants from Qatar University: QUHI-CMED-19/20-1 and GCC # 2017-002 QU/KU.
Languageen
PublisherTaylor & Francis
SubjectEBV
Syrian population
cancer phenotype
colorectal cancer
high-risk HPV
TitleCo-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.
TypeArticle
ESSN2164-554X
dc.accessType Abstract Only


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