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SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections
(
Elsevier
, 2021 , Article)
By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...
Impact of SARS-CoV-2 on Ambient Air Quality in Northwest China (NWC)
(
MDPI
, 2021 , Article)
SARS-CoV-2 was discovered in Wuhan (Hubei) in late 2019 and covered the globe by March 2020. To prevent the spread of the SARS-CoV-2 outbreak, China imposed a countrywide lockdown that significantly improved the air quality. ...
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
(
Elsevier
, 2021 , Article)
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...
Evaluation of antibody response in symptomatic and asymptomatic covid-19 patients and diagnostic assessment of new IgM/IgG elisa kits
(
MDPI
, 2021 , Article)
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This study aims to study the immune response and evaluate the performances of four new IgM and five IgG enzyme-linked immunosorbent assay (ELISA) kits for detecting ...
Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
(
Elsevier
, 2021 , Article)
We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or ...
Prior Statins Use and Risk of Mortality and Severe Disease from COVID-19: A Systematic Review and Meta-Analysis
(
Oxford University Press
, 2021 , Article)
Background
Statins up-regulate angiotensin converting enzyme-2, the receptor of SARS-CoV-2, while also exhibiting pleiotropic antiviral, antithrombotic and anti-inflammatory properties. Uncertainties exist about their ...
Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
(
Frontiers Media
, 2021 , Article)
The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ...
Antibiotics Prescribing in Intensive Care Settings during the COVID-19 Era: A Systematic Review
(
MDPI
, 2021 , Article)
The prevalence of patients admitted to intensive care units (ICUs) with SARS-CoV-2
infection who were prescribed antibiotics is undetermined and might contribute to the increased
global antibiotic resistance. This ...
Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity
(
MDPI
, 2021 , Article)
The COVID-19 pandemic is still posing a devastating threat to social life and economics. Despite the modest decrease in the number of cases during September-November 2020, the number of active cases is on the rise again. ...
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
(
Frontiers Media
, 2021 , Article)
Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...